EP 1180937 A1 20020227 - STRAINS OF BACTERIOPHAGE USEFUL FOR RESCUING PATIENTS INFECTED WITH VANCOMYCIN-RESISTANT ENTEROCOCCUS FAECIUM
Title (en)
STRAINS OF BACTERIOPHAGE USEFUL FOR RESCUING PATIENTS INFECTED WITH VANCOMYCIN-RESISTANT ENTEROCOCCUS FAECIUM
Title (de)
BAKTERIOPHAGENSTÄMME ZUR BEHANDLUNG VON VANCOMYCIN-RESISTENTEM ENTEROCOCCUS FAECIUM INFIZIERTEN PATENTEN
Title (fr)
SOUCHES DE BACTERIOPHAGES UTILES POUR SAUVER DES PATIENTS INFECTES PAR ENTEROCOCCUS FAECIUM RESISTANT A LA VANCOMYCINE
Publication
Application
Priority
- US 0006718 W 20000512
- US 13405599 P 19990513
Abstract (en)
[origin: WO0069269A1] The present invention involves the use of specific phages, designated ENB6 and ENB13, that kill many clinical isolates of vancomycin-resistant Enterococcus faecium and of vancomycin-sensitive Enterococcus faecium. The genome of one of the phage strains, ENB6 has been partially sequenced, and is shown to not contain nucleotide sequences for known bacterial virulence genes or for the vancomycin resistance cassette. Its efficacy in rescuing mice from otherwise-fatal bacteremias is documented herein.
IPC 1-7
IPC 8 full level
C12N 7/00 (2006.01); A61K 9/02 (2006.01); A61K 9/12 (2006.01); A61K 9/72 (2006.01); A61K 35/76 (2015.01); A61K 45/00 (2006.01); A61P 31/04 (2006.01); C12R 1/92 (2006.01)
CPC (source: EP)
A61K 35/76 (2013.01); A61K 39/092 (2013.01); A61P 31/04 (2017.12); C12N 2795/10332 (2013.01)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0069269 A1 20001123; WO 0069269 A9 20020221; AU 4971900 A 20001205; CA 2373486 A1 20001123; EP 1180937 A1 20020227; EP 1180937 A4 20040804; JP 2002543816 A 20021224
DOCDB simple family (application)
US 0006718 W 20000512; AU 4971900 A 20000512; CA 2373486 A 20000512; EP 00931911 A 20000512; JP 2000617737 A 20000512