Global Patent Index - EP 1182263 A1

EP 1182263 A1 20020227 - Process for detecting threonine/serine kinase activity

Title (en)

Process for detecting threonine/serine kinase activity

Title (de)

Verfahren zum Nachweis einer Threonin- oder Serinkinasenaktivität

Title (fr)

Procédé de détection d'une activité thréonine- ou sérine kinase

Publication

EP 1182263 A1 20020227 (EN)

Application

EP 00117457 A 20000811

Priority

EP 00117457 A 20000811

Abstract (en)

The present invention describes a process for detecting threonine or serine kinase activity in an immunoassay using a pre-phosphorylated substrate. <IMAGE>

IPC 1-7

C12Q 1/48; G01N 33/68

IPC 8 full level

C07K 5/083 (2006.01); C07K 5/087 (2006.01); C07K 5/103 (2006.01); C07K 5/107 (2006.01); C12N 9/12 (2006.01); C12Q 1/48 (2006.01); G01N 33/68 (2006.01)

CPC (source: EP US)

C07K 5/081 (2013.01 - EP US); C07K 5/0812 (2013.01 - EP US); C07K 5/1013 (2013.01 - EP US); C07K 5/1016 (2013.01 - EP US); C12N 9/1205 (2013.01 - EP US); C12Q 1/48 (2013.01 - EP US); G01N 33/68 (2013.01 - EP US); G01N 33/6842 (2013.01 - EP US); G01N 33/6845 (2013.01 - EP US); G01N 2333/9121 (2013.01 - EP US)

Citation (search report)

  • [A] WO 9924473 A1 19990520 - HOECHST MARION ROUSSEL DE GMBH [DE], et al
  • [A] US 5733734 A 19980331 - TROJANOWSKI JOHN Q [US], et al
  • [XY] KHOKHLATCHEV ANDREI ET AL: "Reconstitution of mitogen-activated protein kinase phosphorylation cascades in bacteria: Efficient synthesis of active protein kinase.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 272, no. 17, 1997, pages 11057 - 11062, XP002163437, ISSN: 0021-9258
  • [DY] SEETHALA RAMAKRISHNA ET AL: "A fluorescence polarization competition immunoassay for tyrosine kinases", ANALYTICAL BIOCHEMISTRY,ACADEMIC PRESS, SAN DIEGO, CA,US, vol. 255, 15 January 1998 (1998-01-15), pages 257 - 262, XP002150326, ISSN: 0003-2697
  • [Y] WU JINZI J ET AL: "Identification of a high-affinity anti-phosphoserine antibody for the development of a homogeneous fluorescence polarization assay of protein kinase C.", JOURNAL OF BIOMOLECULAR SCREENING, vol. 5, no. 1, February 2000 (2000-02-01), pages 23 - 30, XP000992190, ISSN: 1087-0571
  • [DY] LAWLER SEAN ET AL: "Synergistic activation of SAPK1/JNK1 by two MAP kinase kinases in vitro.", CURRENT BIOLOGY, vol. 8, no. 25, 17 December 1998 (1998-12-17), pages 1387 - 1390, XP000991273, ISSN: 0960-9822
  • [DT] FLEMING YVONNE ET AL: "Synergistic activation of stress-activated protein kinase 1/c-Jun N-terminal kinase (SAPK1/JNK) isoforms by mitogen-activated protein kinase kinase 4 (MKK4) and MKK7.", BIOCHEMICAL JOURNAL, vol. 352, no. 1, 2000, pages 145 - 154, XP000990277, ISSN: 0264-6021

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 0214542 A2 20020221; WO 0214542 A3 20030508; AT E318928 T1 20060315; AU 1213302 A 20020225; DE 60117591 D1 20060427; DE 60117591 T2 20061228; DK 1328657 T3 20060703; EP 1182263 A1 20020227; EP 1328657 A2 20030723; EP 1328657 B1 20060301; US 2003235873 A1 20031225; US 2010021939 A1 20100128

DOCDB simple family (application)

EP 0109186 W 20010808; AT 01980238 T 20010808; AU 1213302 A 20010808; DE 60117591 T 20010808; DK 01980238 T 20010808; EP 00117457 A 20000811; EP 01980238 A 20010808; US 34450903 A 20030708; US 50568009 A 20090720