Global Patent Index - EP 1183266 A4

EP 1183266 A4 20021023 - RETRO-INVERSO PEPTIDES DERIVED FROM LEUKEMIA INHIBITORY FACTOR

Title (en)

RETRO-INVERSO PEPTIDES DERIVED FROM LEUKEMIA INHIBITORY FACTOR

Title (de)

RETROINVERSE PEPTIDE ABGELEITET VOM LEUKÄMIE-HEMMUNGSFAKTOR

Title (fr)

PEPTIDES RETRO INVERSES DERIVES DU FACTEUR D'INHBITION DE LA LEUCEMIE

Publication

EP 1183266 A4 20021023 (EN)

Application

EP 00941527 A 20000616

Priority

  • US 0016760 W 20000616
  • US 13968599 P 19990616

Abstract (en)

[origin: WO0077029A1] Retro-inverso peptides derived from leukemia inhibitory factor (LIF) having between 18 and about 40 amino acids and including the sequence shown in SEQ ID NO: 1. These peptides have the same activity as native LIF and also have neurotrophic activity. Because of the D-amino acid linkage in the peptides, they are less susceptible to proteolytic degradation <i>in vivo</i>.

IPC 1-7

C07K 5/00; A61K 38/00; A61K 35/12

IPC 8 full level

A61K 38/00 (2006.01); A61P 25/00 (2006.01); C07K 7/02 (2006.01); C07K 14/52 (2006.01); C07K 14/54 (2006.01)

CPC (source: EP)

A61P 25/00 (2017.12); A61P 43/00 (2017.12); C07K 7/02 (2013.01); C07K 14/5415 (2013.01); A61K 38/00 (2013.01)

Citation (search report)

  • [A] US 5843892 A 19981201 - PATTERSON PAUL H [US]
  • [A] BRIAND JP ET AL.: "A retro-inverso peptide corresponding to the GH loop of foot-and-mouth disease virus elicits high levels of long-lasting protective neutralizing antibodies", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCE USA, vol. 94, November 1997 (1997-11-01), pages 12545 - 12550, XP002208543
  • [AD] CHOREV M & GOODMAN M: "Recent developments in retro peptides and proteins - an ongoing topochemical exploration", TRENDS IN BIOTECHNOLOGY, vol. 13, October 1995 (1995-10-01), pages 438 - 445, XP002208544
  • See references of WO 0077029A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 0077029 A1 20001221; AU 5622700 A 20010102; CA 2376474 A1 20001221; EP 1183266 A1 20020306; EP 1183266 A4 20021023; IL 147095 A0 20020814; IL 147095 A 20101230; JP 2003502341 A 20030121; JP 2011144184 A 20110728

DOCDB simple family (application)

US 0016760 W 20000616; AU 5622700 A 20000616; CA 2376474 A 20000616; EP 00941527 A 20000616; IL 14709500 A 20000616; IL 14709501 A 20011213; JP 2001503886 A 20000616; JP 2011033594 A 20110218