Global Patent Index - EP 1183267 A4

EP 1183267 A4 20020918 - RETRO-INVERSO PEPTIDES DERIVED FROM INTERLEUKIN-6

Title (en)

RETRO-INVERSO PEPTIDES DERIVED FROM INTERLEUKIN-6

Title (de)

VOM INTERLEUKIN-6 ABGELEITETE RETRO-INVERSO PEPTIDE

Title (fr)

PEPTIDES R TRO-INVERSES D RIV S DE L'INTERLEUKINE 6

Publication

EP 1183267 A4 20020918 (EN)

Application

EP 00952761 A 20000616

Priority

  • US 0040227 W 20000616
  • US 13968799 P 19990616

Abstract (en)

[origin: WO0077033A1] Retro-inverso peptides derived from interleukin-6 (IL-6) having between 17 and about 40 amino acids and including the sequence shown in SEQ ID NO: 1. These peptides have the same activity as native IL-6 and also have neurotrophic activity. Because of the D-amino acid linkage in the peptides, they are less susceptible to proteolytic degradation <i>in vivo</i>.

IPC 1-7

C07K 14/54; A61K 38/20; A61P 25/00

IPC 8 full level

A61K 38/00 (2006.01); A61P 25/00 (2006.01); A61P 25/02 (2006.01); A61P 25/16 (2006.01); A61P 37/04 (2006.01); C07K 7/02 (2006.01); C07K 14/52 (2006.01); C07K 14/54 (2006.01)

CPC (source: EP)

A61P 25/00 (2017.12); A61P 25/02 (2017.12); A61P 25/16 (2017.12); A61P 37/04 (2017.12); C07K 7/02 (2013.01); C07K 14/5412 (2013.01); A61K 38/00 (2013.01)

Citation (search report)

  • [A] WO 9503821 A1 19950209 - BRIEN JOHN S O [US]
  • [A] IHARA S ET AL.: "Identification of Interleukin-6 as a Factor That Induces Neurite Outgrowth by PC12 Cells Primed with NGF", THE JOURNAL OF BIOCHEMISTRY, vol. 120, no. 5, 1996, pages 865 - 868, XP002206392
  • [A] DERETZI G ET AL.: "Suppression of chronic experimental autoimmune neuritis by nasally administered recombinant rat interleukin-6", IMMUNOLOGY, vol. 97, no. 1, May 1999 (1999-05-01), pages 69 - 76, XP002206393
  • See references of WO 0077033A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 0077033 A1 20001221; AU 6540500 A 20010102; CA 2376479 A1 20001221; EP 1183267 A1 20020306; EP 1183267 A4 20020918; IL 147094 A0 20020814; IL 147094 A 20110428; IL 190034 A0 20110801; JP 2003502343 A 20030121; JP 4786843 B2 20111005

DOCDB simple family (application)

US 0040227 W 20000616; AU 6540500 A 20000616; CA 2376479 A 20000616; EP 00952761 A 20000616; IL 14709400 A 20000616; IL 14709401 A 20011213; IL 19003408 A 20080309; JP 2001503890 A 20000616