EP 1185301 A1 20020313 - EMULSION VEHICLE FOR POORLY SOLUBLE DRUGS
Title (en)
EMULSION VEHICLE FOR POORLY SOLUBLE DRUGS
Title (de)
TRÄGEREMULSION FÜR SCHWERLÖSLICHE ARZNEISTOFFE
Title (fr)
EXCIPIENT EN EMULSION POUR MEDICAMENTS FAIBLEMENT SOLUBLES
Publication
Application
Priority
- US 0013572 W 20000517
- US 31749599 A 19990524
- US 31749999 A 19990524
- US 15612899 P 19990927
Abstract (en)
[origin: WO0071163A1] An emulsion of incorporating one or more tocols, a co-solvent and, stabilized by biocompatible surfactants, as a vehicle or carrier for therapeutic drugs, which is substantially ethanol free and which can be administered to animals or humans by various routes is disclosed. Also included in the emulsion is PEGylated vitamin E. PEGylated alpha -tocopherol includes polyethylene glycol subunits attached by a succinic acid diester at the ring hydroxyl of vitamin E and serves as a primary surfactant, stabilizer and a secondary solvent in tocol emulsions.
IPC 1-7
IPC 8 full level
A61K 9/08 (2006.01); A61K 9/107 (2006.01); A61K 9/48 (2006.01); A61K 31/337 (2006.01); A61K 47/10 (2006.01); A61K 47/14 (2006.01); A61K 47/16 (2006.01); A61K 47/20 (2006.01); A61K 47/22 (2006.01); A61K 47/32 (2006.01); A61K 47/34 (2006.01)
CPC (source: EP KR)
A61K 9/0019 (2013.01 - EP); A61K 9/107 (2013.01 - KR); A61K 9/1075 (2013.01 - EP); A61K 47/22 (2013.01 - EP KR)
Citation (search report)
See references of WO 0071163A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0071163 A1 20001130; AU 5273200 A 20001212; BR 0010794 A 20020604; CA 2373994 A1 20001130; EP 1185301 A1 20020313; JP 2003500368 A 20030107; KR 20070058028 A 20070607; MX PA01011981 A 20030904; TW I290052 B 20071121
DOCDB simple family (application)
US 0013572 W 20000517; AU 5273200 A 20000517; BR 0010794 A 20000517; CA 2373994 A 20000517; EP 00937583 A 20000517; JP 2000619464 A 20000517; KR 20077011731 A 20070523; MX PA01011981 A 20000517; TW 89109925 A 20000523