EP 1185556 A1 20020313 - USE OF SOLUBLE PROTEIN MOLECULES EXPRESSED BY THE PANCREAS AND KIDNEY GLOMERULUS
Title (en)
USE OF SOLUBLE PROTEIN MOLECULES EXPRESSED BY THE PANCREAS AND KIDNEY GLOMERULUS
Title (de)
VERWENDUNG VON LÖSLICHEN PROTEINMOLEKÜLEN, DIE IN DER BAUCHSPEICHELDRÜSE UND IM GLOMERULUS DER NIERENRINDE EXPRIMIERT WERDEN
Title (fr)
UTILISATION DE MOLECULES PROTEINIQUES SOLUBLES EXPRIMEES PAR LE PANCREAS ET LE GLOMERULE DE MALPIGHI
Publication
Application
Priority
- FI 0000540 W 20000615
- FI 991369 A 19990615
Abstract (en)
[origin: WO0077044A1] The present invention is related to the of soluble nephrin-like molecules expressed by pancreas and kidney and nucleic acid sequences encoding said nephrin-like molecules, including a human nephrin encoding cDNA, as well as binding substances, capable of specifically recognizing and binding said nephrin-like molecules. The molecules are useful for manufacturing means for diagnostic determination, screening susceptibility of, prophylactic and therapeutic treatment of diabetic and other nephropathies and of diabetes mellitus and other inflammatory and neoplastic pancreatic diseases. The invention is further characterized by the fact that the soluble nephrin-like molecules, binding substances specifically recognizing said soluble nephrin-like molecules can be used to make the diagnostic evaluation from a blood, serum and/or urine sample.
IPC 1-7
IPC 8 full level
C07K 14/705 (2006.01); C07K 16/28 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01)
CPC (source: EP)
C07K 14/70525 (2013.01); C07K 16/2803 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01)
Citation (search report)
See references of WO 0077044A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0077044 A1 20001221; AU 5225300 A 20010102; CA 2374000 A1 20001221; EP 1185556 A1 20020313; FI 991369 A0 19990615; HK 1044781 A1 20021101
DOCDB simple family (application)
FI 0000540 W 20000615; AU 5225300 A 20000615; CA 2374000 A 20000615; EP 00936934 A 20000615; FI 991369 A 19990615; HK 02106477 A 20020902