Global Patent Index - EP 1185556 A1

EP 1185556 A1 20020313 - USE OF SOLUBLE PROTEIN MOLECULES EXPRESSED BY THE PANCREAS AND KIDNEY GLOMERULUS

Title (en)

USE OF SOLUBLE PROTEIN MOLECULES EXPRESSED BY THE PANCREAS AND KIDNEY GLOMERULUS

Title (de)

VERWENDUNG VON LÖSLICHEN PROTEINMOLEKÜLEN, DIE IN DER BAUCHSPEICHELDRÜSE UND IM GLOMERULUS DER NIERENRINDE EXPRIMIERT WERDEN

Title (fr)

UTILISATION DE MOLECULES PROTEINIQUES SOLUBLES EXPRIMEES PAR LE PANCREAS ET LE GLOMERULE DE MALPIGHI

Publication

EP 1185556 A1 20020313 (EN)

Application

EP 00936934 A 20000615

Priority

  • FI 0000540 W 20000615
  • FI 991369 A 19990615

Abstract (en)

[origin: WO0077044A1] The present invention is related to the of soluble nephrin-like molecules expressed by pancreas and kidney and nucleic acid sequences encoding said nephrin-like molecules, including a human nephrin encoding cDNA, as well as binding substances, capable of specifically recognizing and binding said nephrin-like molecules. The molecules are useful for manufacturing means for diagnostic determination, screening susceptibility of, prophylactic and therapeutic treatment of diabetic and other nephropathies and of diabetes mellitus and other inflammatory and neoplastic pancreatic diseases. The invention is further characterized by the fact that the soluble nephrin-like molecules, binding substances specifically recognizing said soluble nephrin-like molecules can be used to make the diagnostic evaluation from a blood, serum and/or urine sample.

IPC 1-7

C07K 14/47; C07K 16/18; G01N 33/68

IPC 8 full level

C07K 14/705 (2006.01); C07K 16/28 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01)

CPC (source: EP)

C07K 14/70525 (2013.01); C07K 16/2803 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01)

Citation (search report)

See references of WO 0077044A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 0077044 A1 20001221; AU 5225300 A 20010102; CA 2374000 A1 20001221; EP 1185556 A1 20020313; FI 991369 A0 19990615; HK 1044781 A1 20021101

DOCDB simple family (application)

FI 0000540 W 20000615; AU 5225300 A 20000615; CA 2374000 A 20000615; EP 00936934 A 20000615; FI 991369 A 19990615; HK 02106477 A 20020902