Global Patent Index - EP 1189882 A1

EP 1189882 A1 20020327 - BIPHENYL BUTYRIC ACID DERIVATIVE AS A MATRIX METALLOPROTEINASE INHIBITOR

Title (en)

BIPHENYL BUTYRIC ACID DERIVATIVE AS A MATRIX METALLOPROTEINASE INHIBITOR

Title (de)

BIPHENYL-BUTANSÄURE-DERIVATE ALS INHIBITOREN DER MATRIX-METALLOPROTEINASE

Title (fr)

DERIVES D'ACIDE DIPHENYLBUTYRIQUE INHIBITEURS DE METALLOPROTEINASE MATRICIELLE

Publication

EP 1189882 A1 20020327 (EN)

Application

EP 01926225 A 20010424

Priority

  • KR 0100687 W 20010424
  • KR 20000021834 A 20000425
  • KR 20000021835 A 20000425

Abstract (en)

[origin: WO0183445A1] The present invention provides a novel biphenyl butyric acid derivative, isomer and pharmaceutically acceptable salts thereof which are useful as an inhibitor of matrix metalloproteinase (MMP) and a process for preparing the same. Since the biphenyl butyric acid derivative of the invention selectively inhibits the activity of MMP in vitro, it can be practically applied to the treatment and prevention of diseases caused by overexpression of MMP.

IPC 1-7

C07D 207/00

IPC 8 full level

C07D 295/18 (2006.01); A61K 31/192 (2006.01); A61K 31/36 (2006.01); A61K 31/40 (2006.01); A61K 31/472 (2006.01); A61K 31/495 (2006.01); A61K 31/5375 (2006.01); A61P 1/02 (2006.01); A61P 1/16 (2006.01); A61P 9/10 (2006.01); A61P 11/00 (2006.01); A61P 19/02 (2006.01); A61P 19/08 (2006.01); A61P 29/00 (2006.01); A61P 35/04 (2006.01); A61P 37/02 (2006.01); A61P 43/00 (2006.01); C07C 231/02 (2006.01); C07C 235/78 (2006.01); C07C 237/04 (2006.01); C07C 237/22 (2006.01); C07C 237/42 (2006.01); C07C 255/60 (2006.01); C07D 207/16 (2006.01); C07D 217/26 (2006.01); C07D 295/185 (2006.01); C07D 295/192 (2006.01); C07D 317/50 (2006.01); C07D 317/60 (2006.01)

CPC (source: EP)

A61P 1/02 (2017.12); A61P 1/16 (2017.12); A61P 9/10 (2017.12); A61P 11/00 (2017.12); A61P 19/02 (2017.12); A61P 19/08 (2017.12); A61P 29/00 (2017.12); A61P 35/04 (2017.12); A61P 37/02 (2017.12); A61P 43/00 (2017.12); C07C 235/78 (2013.01); C07C 237/22 (2013.01); C07C 237/42 (2013.01); C07C 255/60 (2013.01); C07D 207/16 (2013.01); C07D 217/26 (2013.01); C07D 295/185 (2013.01); C07D 295/192 (2013.01); C07D 317/60 (2013.01); C07C 2601/02 (2017.04)

Citation (search report)

See references of WO 0183445A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

DOCDB simple family (publication)

WO 0183445 A1 20011108; AU 5275901 A 20011112; CA 2377629 A1 20011108; CN 1366518 A 20020828; EP 1189882 A1 20020327; JP 2003531894 A 20031028

DOCDB simple family (application)

KR 0100687 W 20010424; AU 5275901 A 20010424; CA 2377629 A 20010424; CN 01801067 A 20010424; EP 01926225 A 20010424; JP 2001580874 A 20010424