EP 1190084 A1 20020327 - REGULATION SYSTEM OF EXPRESSION USING NUCLEAR PPAR RECEPTORS
Title (en)
REGULATION SYSTEM OF EXPRESSION USING NUCLEAR PPAR RECEPTORS
Title (de)
EXPRESSIONSREGULIERUNGSSYSTEM MITTELS PPAR KERNREZEPTORS
Title (fr)
SYSTEME DE REGULATION DE L'EXPRESSION UTILISANT LES RECEPTEURS NUCLEAIRES PPAR
Publication
Application
Priority
- FR 0001744 W 20000622
- FR 9907957 A 19990622
- US 14972199 P 19990820
Abstract (en)
[origin: WO0078986A1] The invention concerns novel methods and compositions for the pharmacological regulation of the expression of transgenes. More particularly, it concerns a composition comprising: (a) a first element comprising a nucleic acid of interest under the control of an inducible promoter comprising an element containing a response element to a PPAR and a minimal transcriptional receptor; and (b) a second element comprising a nucleic acid coding for a PPAR under the control of a transcriptional promoter, for simultaneous, separate or prolonged use. The invention concerns the use of said compositions and methods in the experimental, clinical, therapeutic or diagnostic fields.
IPC 1-7
IPC 8 full level
A61K 35/76 (2006.01); A61K 38/22 (2006.01); A61K 48/00 (2006.01); C07K 14/705 (2006.01); C12N 15/09 (2006.01); C12N 5/10 (2006.01); C12N 15/85 (2006.01); C12Q 1/68 (2006.01)
CPC (source: EP KR)
A61K 48/00 (2013.01 - EP); C07K 14/705 (2013.01 - EP); C12N 15/85 (2013.01 - EP KR); C12N 2830/002 (2013.01 - EP); C12N 2830/008 (2013.01 - EP); C12N 2830/42 (2013.01 - EP); C12N 2830/85 (2013.01 - EP); C12N 2840/20 (2013.01 - EP)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0078986 A1 20001228; WO 0078986 B1 20010419; AU 6164500 A 20010109; BR 0011897 A 20020326; CA 2375869 A1 20001228; CN 1370240 A 20020918; CZ 20014609 A3 20020515; EP 1190084 A1 20020327; HU P0203584 A2 20030228; IL 147104 A0 20020814; JP 2003503034 A 20030128; KR 20020028909 A 20020417; MX PA01013227 A 20020604; NO 20016347 D0 20011221; NO 20016347 L 20020219; NZ 516678 A 20040430
DOCDB simple family (application)
FR 0001744 W 20000622; AU 6164500 A 20000622; BR 0011897 A 20000622; CA 2375869 A 20000622; CN 00811928 A 20000622; CZ 20014609 A 20000622; EP 00948058 A 20000622; HU P0203584 A 20000622; IL 14710400 A 20000622; JP 2001505726 A 20000622; KR 20017016447 A 20011221; MX PA01013227 A 20000622; NO 20016347 A 20011221; NZ 51667800 A 20000622