EP 1191940 A4 20030402 - TUMOR NECROSIS FACTOR RECEPTOR 5
Title (en)
TUMOR NECROSIS FACTOR RECEPTOR 5
Title (de)
TUMORNEKROSEFAKTOR REZEPTOR 5
Title (fr)
RECEPTEUR 5 DU FACTEUR DE NECROSE TUMORALE
Publication
Application
Priority
- US 0013515 W 20000518
- US 13516499 P 19990520
Abstract (en)
[origin: WO0071150A1] The present invention relates to a novel human gene encoding a polypeptide which is a member of the TNF receptor family, and has now been found to bind TRAIL. More specifically, an isolated nucleic acid molecule is provided encoding a human polypeptide named tumor necrosis factor receptor-5, sometimes referred to as "TNFR-5" or "TR5", and now referred to hereinafter as "TRAIL receptor without intracellular domain" or "TRID". TRID polypeptides are also provided, as are vectors, host cells, and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists or antagonists of TRAIL polypeptide activity. Also provided are diagnostic and therapeutic methods utilizing such compositions.
IPC 1-7
IPC 8 full level
A61K 31/164 (2006.01); A61K 31/436 (2006.01); A61K 31/52 (2006.01); A61K 31/573 (2006.01); A61K 31/66 (2006.01); A61K 31/711 (2006.01); A61K 38/00 (2006.01); A61K 38/21 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61P 1/04 (2006.01); A61P 1/16 (2006.01); A61P 3/10 (2006.01); A61P 5/14 (2006.01); A61P 7/00 (2006.01); A61P 7/06 (2006.01); A61P 9/10 (2006.01); A61P 11/06 (2006.01); A61P 13/12 (2006.01); A61P 17/02 (2006.01); A61P 17/06 (2006.01); A61P 19/00 (2006.01); A61P 19/02 (2006.01); A61P 19/10 (2006.01); A61P 21/04 (2006.01); A61P 25/16 (2006.01); A61P 25/28 (2006.01); A61P 27/02 (2006.01); A61P 29/00 (2006.01); A61P 31/04 (2006.01); A61P 31/12 (2006.01); A61P 31/16 (2006.01); A61P 31/18 (2006.01); A61P 31/22 (2006.01); A61P 33/00 (2006.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01); A61P 37/02 (2006.01); A61P 37/06 (2006.01); A61P 37/08 (2006.01); C07K 14/705 (2006.01); C07K 16/28 (2006.01); C07K 19/00 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12P 21/08 (2006.01)
CPC (source: EP)
A61P 1/04 (2017.12); A61P 1/16 (2017.12); A61P 3/10 (2017.12); A61P 5/14 (2017.12); A61P 7/00 (2017.12); A61P 7/06 (2017.12); A61P 9/10 (2017.12); A61P 11/06 (2017.12); A61P 13/12 (2017.12); A61P 17/02 (2017.12); A61P 17/06 (2017.12); A61P 19/00 (2017.12); A61P 19/02 (2017.12); A61P 19/10 (2017.12); A61P 21/04 (2017.12); A61P 25/16 (2017.12); A61P 25/28 (2017.12); A61P 27/02 (2017.12); A61P 29/00 (2017.12); A61P 31/04 (2017.12); A61P 31/12 (2017.12); A61P 31/16 (2017.12); A61P 31/18 (2017.12); A61P 31/22 (2017.12); A61P 33/00 (2017.12); A61P 35/00 (2017.12); A61P 35/02 (2017.12); A61P 37/02 (2017.12); A61P 37/06 (2017.12); A61P 37/08 (2017.12); C07K 14/70578 (2013.01); C07K 16/2878 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01); C07K 2319/00 (2013.01); C07K 2319/30 (2013.01); C12N 2799/026 (2013.01)
Citation (search report)
- [X] EP 0867509 A2 19980930 - SMITHKLINE BEECHAM CORP [US]
- [X] WO 9830693 A2 19980716 - HUMAN GENOME SCIENCES INC [US], et al
- [X] WO 9900423 A1 19990107 - IMMUNEX CORP [US]
- [PX] WO 9946287 A1 19990916 - GENETICS INST [US]
- See references of WO 0071150A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0071150 A1 20001130; AU 5022400 A 20001212; CA 2374674 A1 20001130; EP 1191940 A1 20020403; EP 1191940 A4 20030402; JP 2003502287 A 20030121
DOCDB simple family (application)
US 0013515 W 20000518; AU 5022400 A 20000518; CA 2374674 A 20000518; EP 00932514 A 20000518; JP 2000619452 A 20000518