EP 1192177 A1 20020403 - STATINE-DERIVED TETRAPEPTIDE INHIBITORS OF BETA-SECRETASE
Title (en)
STATINE-DERIVED TETRAPEPTIDE INHIBITORS OF BETA-SECRETASE
Title (de)
STATIN-ABSTAMMENDE TETRAPEPTIDE ALS INHIBITOREN DER BETA-SECRETASE
Title (fr)
INHIBITEURS TETRAPEPTIDES DERIVES DE LA STATINE DE BETA-SECRETASE
Publication
Application
Priority
- US 0016643 W 20000615
- US 13917399 P 19990615
Abstract (en)
[origin: WO0077030A1] Statine-derived peptide inhibitors of the beta -secretase enzyme are provided which are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention provide useful methods of treatment by administration of these inhibitors to reduce A beta peptide formation and pharmaceutical compositions.
IPC 1-7
IPC 8 full level
A61K 38/55 (2006.01); A61P 25/28 (2006.01); A61P 43/00 (2006.01); C07K 5/02 (2006.01); C07K 5/027 (2006.01); C07K 7/02 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP)
A61P 25/28 (2017.12); A61P 43/00 (2017.12); C07K 5/0205 (2013.01); A61K 38/00 (2013.01)
Citation (search report)
See references of WO 0077030A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0077030 A1 20001221; AU 5619400 A 20010102; CA 2376420 A1 20001221; EP 1192177 A1 20020403; JP 2003502342 A 20030121
DOCDB simple family (application)
US 0016643 W 20000615; AU 5619400 A 20000615; CA 2376420 A 20000615; EP 00941491 A 20000615; JP 2001503887 A 20000615