EP 1194576 A1 20020410 - DELIVERY SYSTEM
Title (en)
DELIVERY SYSTEM
Title (de)
DAREICHUNGSSYSTEM
Title (fr)
SYSTEME D'ADMINISTRATION
Publication
Application
Priority
- GB 9914960 A 19990625
- IB 0000974 W 20000623
Abstract (en)
[origin: WO0100857A1] The invention relates to delivery systems for heterologous antigens. Chromosomal loci within rRNA operons such as those of the 16S or the 23S genes have been identified as useful sites for the integration of nucleic acids into the chromosome of <i>Vibrio cholerae</i> bacteria. A particularly useful regulatory sequence for the direction of high level expression of heterologous antigens in this bacterium has been identified as the <i>OmpU</i> promoter.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); A61K 39/00 (2006.01); A61K 39/106 (2006.01); A61P 31/04 (2006.01); A61P 31/12 (2006.01); C12N 1/21 (2006.01); C12N 15/63 (2006.01); C12N 15/74 (2006.01); C12N 15/90 (2006.01); C12R 1/63 (2006.01)
CPC (source: EP)
A61P 31/04 (2017.12); A61P 31/12 (2017.12); C12N 15/63 (2013.01); C12N 15/74 (2013.01); C12N 15/902 (2013.01); Y02A 50/30 (2017.12)
Citation (search report)
See references of WO 0100857A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0100857 A1 20010104; CA 2377534 A1 20010104; EP 1194576 A1 20020410; GB 9914960 D0 19990825; JP 2003503066 A 20030128
DOCDB simple family (application)
IB 0000974 W 20000623; CA 2377534 A 20000623; EP 00942323 A 20000623; GB 9914960 A 19990625; JP 2001506849 A 20000623