EP 1196435 A1 20020417 - RECOMBINANT ADENOVIRUS
Title (en)
RECOMBINANT ADENOVIRUS
Title (de)
REKOMBINANTES ADENOVIRUS
Title (fr)
ADENOVIRUS RECOMBINANT
Publication
Application
Priority
- SE 0001390 W 20000630
- SE 9902601 A 19990706
- US 14363299 P 19990714
Abstract (en)
[origin: WO0102431A1] Recombinant adenovirus with changed tropism. In the adenovirus the native pentone fibre, comprising a fibre tail, a fibre shaft and a fibre knob including a trimerisation motif, has been changed in that the native knob containing the cell binding structure and the native trimerisation motif has been removed and a new cellbinding ligand and an external trimerisation motif have been introduced into the virus fiber. Further, the invention relates to the recombinant adenovirus for the treatment of human diseases, either in vivo or by in vitro methods and also to a method for rescuing of recombinant adenovirus fibers into the adenovirus genome.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); A61K 35/76 (2006.01); A61K 38/00 (2006.01); A61K 38/43 (2006.01); A61K 38/46 (2006.01); A61K 48/00 (2006.01); A61P 35/00 (2006.01); C12N 7/00 (2006.01); C12N 15/861 (2006.01)
CPC (source: EP KR)
A61P 35/00 (2017.12 - EP); C07K 14/005 (2013.01 - EP); C12N 7/00 (2013.01 - KR); C12N 15/86 (2013.01 - EP); C12N 2710/10322 (2013.01 - EP); C12N 2710/10343 (2013.01 - EP); C12N 2710/10345 (2013.01 - EP); C12N 2810/405 (2013.01 - EP); C12N 2810/851 (2013.01 - EP); C12N 2810/854 (2013.01 - EP); C12N 2810/855 (2013.01 - EP); C12N 2810/859 (2013.01 - EP)
Citation (search report)
See references of WO 0102431A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0102431 A1 20010111; AU 6040100 A 20010122; AU 763733 B2 20030731; CA 2378324 A1 20010111; CN 1359391 A 20020717; EP 1196435 A1 20020417; JP 2003531568 A 20031028; KR 20020092886 A 20021212
DOCDB simple family (application)
SE 0001390 W 20000630; AU 6040100 A 20000630; CA 2378324 A 20000630; CN 00809885 A 20000630; EP 00946680 A 20000630; JP 2001508218 A 20000630; KR 20027000132 A 20020105