EP 1196611 A1 20020417 - REGULATION OF CARBON ASSIMILATION
Title (en)
REGULATION OF CARBON ASSIMILATION
Title (de)
REGULIERUNG VON KOHLENSTOFFASSIMILATION
Title (fr)
REGULATION DE L'ASSIMILATION DU CARBONE
Publication
Application
Priority
US 9914437 W 19990629
Abstract (en)
[origin: WO0100852A1] The present invention provides a method of increasing the productivity of a microorganism by improving the assimilation of carbon dioxide. Specifically, the invention provides a polypeptide having phosphoenolpyruvate carboxylase activity which does not require acetyl coenzyme A for activation and is desensitized to feedback inhibition by aspartic acid, and to genes coding for this polypeptide. A gene encoding a PEP carboxylase that is not regulated by acetyl-CoA or aspartic acid can improve carbon flow from the three carbon intermediate PEP to the four carbon intermediate OAA, contribute to compounds derived from OAA, and increase amino acid biosynthesis. The invention further provides recombinant DNA molecules containing these genes, bacteria transformed with these genes, and a method of producing amino acids using the transformed bacteria.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); C12N 1/21 (2006.01); C12N 9/88 (2006.01); C12N 15/60 (2006.01); C12P 1/00 (2006.01); C12P 7/40 (2006.01); C12P 13/04 (2006.01); C12P 13/08 (2006.01); C12R 1/15 (2006.01)
CPC (source: EP KR)
C12N 9/88 (2013.01 - EP); C12N 15/52 (2013.01 - KR); C12P 1/00 (2013.01 - EP); C12P 7/40 (2013.01 - EP); C12P 13/04 (2013.01 - EP); C12P 13/08 (2013.01 - EP)
Citation (search report)
See references of WO 0100852A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0100852 A1 20010104; AU 4720999 A 20010131; CA 2377488 A1 20010104; CN 1373810 A 20021009; EP 1196611 A1 20020417; JP 2003503064 A 20030128; KR 20020015708 A 20020228; MX PA01013445 A 20020730
DOCDB simple family (application)
US 9914437 W 19990629; AU 4720999 A 19990629; CA 2377488 A 19990629; CN 99816826 A 19990629; EP 99930732 A 19990629; JP 2001506844 A 19990629; KR 20017016799 A 20011228; MX PA01013445 A 19990629