EP 1196773 A1 20020417 - E4ORF4 AND PP2A POLYPEPTIDES, MODULATORS, AND MIMETICS FOR SELECTIVELY INDUCING CELL DEATH
Title (en)
E4ORF4 AND PP2A POLYPEPTIDES, MODULATORS, AND MIMETICS FOR SELECTIVELY INDUCING CELL DEATH
Title (de)
E4ORF4 UND PPA2 POLYPEPTIDE, MODULATOREN UND MIMETIKA ZUR SELEKTIVEN INDUZIERUNG VON ZELLTOD
Title (fr)
POLYPEPTIDES, MODULATEURS ET MIMETIQUES E4ORF4 ET PP2A PERMETTANT D'INDUIRE UNE MORT CELLULAIRE SELECTIVE
Publication
Application
Priority
- CA 0000817 W 20000711
- US 35160299 A 19990712
Abstract (en)
[origin: WO0104629A1] Disclosed is the ability of the adenovirus protein, E4orf4, to induce cell death in neoplastic cells, but not in non-neoplastic cells. This discovery allows for the generation of anti-neoplastic therapeutic reagents and compounds. In addition, the invention provides methods for screening for E4orf4 analogs having anti-neoplastic properties.
IPC 1-7
IPC 8 full level
A61K 38/46 (2006.01); A61P 35/00 (2006.01); C12Q 1/02 (2006.01); C12Q 1/42 (2006.01); G01N 33/50 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01)
CPC (source: EP)
A61K 38/465 (2013.01); A61P 35/00 (2017.12); C12Q 1/025 (2013.01); C12Q 1/42 (2013.01); C12Y 301/03016 (2013.01); G01N 33/5011 (2013.01); A61K 48/00 (2013.01); A61K 2039/505 (2013.01); G01N 2510/00 (2013.01)
Citation (search report)
See references of WO 0104629A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0104629 A1 20010118; WO 0104629 A9 20020829; AU 5959200 A 20010130; CA 2377228 A1 20010118; EP 1196773 A1 20020417
DOCDB simple family (application)
CA 0000817 W 20000711; AU 5959200 A 20000711; CA 2377228 A 20000711; EP 00945500 A 20000711