EP 1198468 A1 20020424 - STABILIZED VIRAL ENVELOPE PROTEINS AND USES THEREOF
Title (en)
STABILIZED VIRAL ENVELOPE PROTEINS AND USES THEREOF
Title (de)
STABILISIERTE VIRALE BRIEFUMSCHLAG-PROTEINE UND IHRE VERWENDUNGEN
Title (fr)
PROTEINES D'ENVELOPPE VIRALE STABILISEE ET UTILISATIONS
Publication
Application
Priority
- US 0017267 W 20000623
- US 34099299 A 19990625
Abstract (en)
[origin: WO0100648A1] This invention provides an isolated nucleic acid which comprises a nucleotide segment having a sequence encoding a viral envelope protein comprising a viral surface protein and a corresponding viral transmembrane protein wherein the viral envelope protein contains one or more mutations in amino acid sequence that enhance the stability of the complex formed between the viral surface protein and transmembrane protein. This invention also provide a viral envelope protein comprising a viral surface protein and a corresponding viral transmembrane protein wherein the viral envelope protein contains one or more mutations in amino acid sequence that enhance the stability of the complex formed between the viral surface protein and transmembrane protein. This invention further provides methods of treating HIV-1 infection.
IPC 1-7
C07H 21/04; C07K 16/00; C07K 14/00; A01N 37/18; A01N 1/00; A61K 38/16; C12Q 1/68; G01N 33/53; C12P 21/06; C12N 15/00
IPC 8 full level
C12N 15/09 (2006.01); A61K 31/711 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61P 31/18 (2006.01); C07K 14/16 (2006.01); C07K 16/10 (2006.01); C07K 19/00 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 7/00 (2006.01); C12P 21/08 (2006.01); A61K 39/00 (2006.01)
CPC (source: EP)
A61P 31/18 (2018.01); C07K 16/1063 (2013.01); A61K 39/00 (2013.01); A61K 2039/53 (2013.01)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0100648 A1 20010104; AU 5884200 A 20010131; AU 782123 B2 20050707; CA 2370517 A1 20010104; EP 1198468 A1 20020424; EP 1198468 A4 20030730; HK 1046911 A1 20030130; JP 2003509013 A 20030311
DOCDB simple family (application)
US 0017267 W 20000623; AU 5884200 A 20000623; CA 2370517 A 20000623; EP 00944801 A 20000623; HK 02107688 A 20021023; JP 2001507055 A 20000623