EP 1198576 A1 20020424 - SINK PROTEIN
Title (en)
SINK PROTEIN
Title (de)
"SENKEN"-PROTEIN
Title (fr)
PROTEINE PUITS
Publication
Application
Priority
- EP 00952058 A 20000728
- EP 99202524 A 19990730
- NL 0000541 W 20000728
Abstract (en)
[origin: EP1074629A1] The invention relates to the field of providing additional nutritional value to a (micro-)organism by equipping a cell or cells of said organism with means for producing desired levels of an amino acid, preferably a so-called essential amino acid. The invention provides a method for regulating the flux, concentration or biosynthesis of a desired amino acid in a cell comprising providing said cell with a nucleic acid encoding a proteinaceous substance comprising at least said amino acid, such a proteinaceous substance herein also called sink protein whereby sink stands for the capacity of said proteinaceous substance to function as sink or reservoir for the desired amino acid, thereby regulating or reducing the amount or concentration of available of free amino acid in said cell by binding it through transcription and translation processes to the sink protein encoded by the additional nucleic acid.
IPC 1-7
IPC 8 full level
A01H 5/00 (2006.01); C12N 5/10 (2006.01); C12N 15/82 (2006.01); C12P 13/08 (2006.01); C12P 13/12 (2006.01); C12P 13/22 (2006.01)
CPC (source: EP)
C12N 15/8251 (2013.01); C12N 15/8253 (2013.01); C12N 15/8254 (2013.01); C12P 13/08 (2013.01); C12P 13/12 (2013.01); C12P 13/227 (2013.01)
Citation (search report)
See references of WO 0109359A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
EP 1074629 A1 20010207; AU 6481900 A 20010219; CA 2381556 A1 20010208; CN 1377416 A 20021030; EP 1198576 A1 20020424; WO 0109359 A1 20010208
DOCDB simple family (application)
EP 99202524 A 19990730; AU 6481900 A 20000728; CA 2381556 A 20000728; CN 00813534 A 20000728; EP 00952058 A 20000728; NL 0000541 W 20000728