EP 1198592 A4 20020918 - OLIGONUCLEOTIDES INCORPORATING BOTH 2-AMINOADENINE AND 5-SUBSTITUTED PYRIMIDINES
Title (en)
OLIGONUCLEOTIDES INCORPORATING BOTH 2-AMINOADENINE AND 5-SUBSTITUTED PYRIMIDINES
Title (de)
OLIGONUCLEOTIDE DIE 2-AMINOADENIN UND 5-SUBSTITUIERTE PYRIMIDINE ENTHALTEN.
Title (fr)
OLIGONUCLEOTIDES COMPORTANT A LA FOIS 2-AMINOADENINE ET PYRIMIDINES 5-SUBSTITUEES
Publication
Application
Priority
- US 0018415 W 20000705
- US 34810699 A 19990706
Abstract (en)
[origin: WO0102608A1] This invention presents oligonucleotides incorporating both 2-aminoadenine and 5-substituted pyrimidines together with a modified internucleoside linkage. In certain preferred embodiments, the 5-substituted pyrimidine is 5-methylcytosine. The oligonucleotides produced provide stronger hybridization to their target sequences. These oligonucleotides can be useful compounds, <i>inter alia</i> for diagnostic and therapeutic applications.
IPC 1-7
C12Q 1/68; C12P 19/34; C07H 21/00; C07H 21/02; C07H 21/04; A01N 43/04; A61K 31/70
IPC 8 full level
C07H 21/00 (2006.01); C12N 15/113 (2010.01)
CPC (source: EP)
C07H 21/00 (2013.01); C12N 15/113 (2013.01); C12N 2310/315 (2013.01); C12N 2310/321 (2013.01); C12N 2310/333 (2013.01); C12N 2310/334 (2013.01); C12N 2310/3341 (2013.01); C12N 2310/335 (2013.01); C12N 2310/346 (2013.01)
Citation (search report)
- [Y] WO 9839353 A1 19980911 - PERKIN ELMER CORP [US]
- [Y] WO 9402501 A1 19940203 - ISIS PHARMACEUTICALS INC [US], et al
- [Y] EP 0431523 A2 19910612 - ENZO BIOCHEM INC [US]
- See references of WO 0102608A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0102608 A1 20010111; AU 6071300 A 20010122; EP 1198592 A1 20020424; EP 1198592 A4 20020918
DOCDB simple family (application)
US 0018415 W 20000705; AU 6071300 A 20000705; EP 00947043 A 20000705