EP 1202714 A1 20020508 - VINYL ETHER LIPIDS WITH CLEAVABLE HYDROPHILIC HEADGROUPS
Title (en)
VINYL ETHER LIPIDS WITH CLEAVABLE HYDROPHILIC HEADGROUPS
Title (de)
VINYLETHERLIPIDE MIT SPALTBAREN HYDROPHILEN KOPFGRUPPEN
Title (fr)
LIPIDES D'ETHER VINYLIQUES AVEC DES GROUPES DE TETES HYDROPHILES CLIVABLES
Publication
Application
Priority
- US 0019430 W 20000717
- US 14430199 P 19990716
- US 14655299 P 19990730
Abstract (en)
[origin: WO0105375A1] A novel amphiphilic lipid compound having a cleavable, vinyl ether linked hydrophilic headgroup is described. Also described are liposomes containing the vinyl ether lipid compound, which may be triggered to release their contents and/or permeablize or fuse with target lipid membranes. The cleavable vinyl ether linkage allows the hydrophilic headgroup to be dissociated from the hydrophobic tailgroup(s) of the lipid compound to facilitate phase transitions in the lipid bilayer.
IPC 1-7
IPC 8 full level
A61K 9/127 (2006.01)
CPC (source: EP)
A61K 9/1272 (2013.01)
Citation (search report)
See references of WO 0105375A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0105375 A1 20010125; AU 6105300 A 20010205; EP 1202714 A1 20020508
DOCDB simple family (application)
US 0019430 W 20000717; AU 6105300 A 20000717; EP 00947445 A 20000717