Global Patent Index - EP 1202737 A2

EP 1202737 A2 20020508 - ANTIVIRAL THERAPY USE OF P-GLYCOPROTEIN MODULATORS

Title (en)

ANTIVIRAL THERAPY USE OF P-GLYCOPROTEIN MODULATORS

Title (de)

VERWENDUNG VON P-GLYCOPROTEINMODULATOREN IN DER ANTIVIRALEN THERAPIE

Title (fr)

UTILISATION DE MODULATEURS DE P-GLYCOPROTEINE DANS UN TRAITEMENT ANTIVIRAL

Publication

EP 1202737 A2 20020508 (EN)

Application

EP 00967364 A 20000807

Priority

  • US 0040588 W 20000807
  • US 37026699 A 19990809

Abstract (en)

[origin: WO0110387A2] The present invention relates to a pharmaceutical composition comprising a 10, 11 methanodibenzosuberane and use thereof for the treatment of HIV infection. Co-administration of the 10, 11 methanodibenzosuberane with an HIV protease inhibitor increases the concentration of the protease inhibitor in certain tissues, including the brain and testes, without substantially increasing plasma levels of the protease inhibitor. Accordingly, additional antiviral therapy can be achieved without use of increased drug dosages, thereby reducing the potential for occurrence of undesirable side effects deriving from drug toxicity.

IPC 1-7

A61K 31/495; A61K 31/50; A61K 31/205; A61K 31/24; A61K 31/22; A61K 31/195; A61K 31/20

IPC 8 full level

A61K 45/00 (2006.01); A61K 31/34 (2006.01); A61K 31/341 (2006.01); A61K 31/427 (2006.01); A61K 31/445 (2006.01); A61K 31/47 (2006.01); A61K 31/472 (2006.01); A61K 31/4725 (2006.01); A61K 31/495 (2006.01); A61K 31/496 (2006.01); A61K 38/55 (2006.01); A61P 31/18 (2006.01); A61P 43/00 (2006.01)

CPC (source: EP)

A61K 31/34 (2013.01); A61K 31/445 (2013.01); A61K 31/47 (2013.01); A61K 31/495 (2013.01); A61K 38/55 (2013.01); A61P 31/18 (2017.12); A61P 43/00 (2017.12)

C-Set (source: EP)

  1. A61K 38/55 + A61K 31/495
  2. A61K 38/55 + A61K 2300/00
  3. A61K 31/495 + A61K 31/495
  4. A61K 31/495 + A61K 31/47
  5. A61K 31/495 + A61K 31/445
  6. A61K 31/495 + A61K 31/34
  7. A61K 31/34 + A61K 2300/00
  8. A61K 31/445 + A61K 2300/00
  9. A61K 31/47 + A61K 2300/00
  10. A61K 31/495 + A61K 2300/00

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 0110387 A2 20010215; WO 0110387 A3 20010823; AU 7757400 A 20010305; CA 2378984 A1 20010215; EP 1202737 A2 20020508; EP 1202737 A4 20050302; JP 2003523944 A 20030812

DOCDB simple family (application)

US 0040588 W 20000807; AU 7757400 A 20000807; CA 2378984 A 20000807; EP 00967364 A 20000807; JP 2001514912 A 20000807