EP 1203024 A4 20030226 - HUMAN TUMOR NECROSIS FACTOR RECEPTORS TR13 AND TR14
Title (en)
HUMAN TUMOR NECROSIS FACTOR RECEPTORS TR13 AND TR14
Title (de)
HUMANE TUMORNEKROSEFAKTOR REZEPTOREN TR13 UND TR14
Title (fr)
RECEPTEURS DU FACTEUR DE NECROSE DES TUMEURS HUMAIN TR13 ET TR14
Publication
Application
Priority
- US 0019343 W 20000714
- US 14408799 P 19990716
- US 14945099 P 19990818
- US 14971299 P 19990820
- US 15308999 P 19990910
Abstract (en)
[origin: WO0105834A1] The present invention relates to two novel members of the tumor necrosis factor family of receptors. More specifically, isolated nucleic acid molecules are provided encoding the novel human necrosis factor receptors, TR13 and TR14. TR13 and TR14 polypeptides are also provided, as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of TR13 and/or TR14 activity.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); A61K 38/00 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61P 1/02 (2006.01); A61P 1/04 (2006.01); A61P 1/14 (2006.01); A61P 1/16 (2006.01); A61P 3/10 (2006.01); A61P 7/00 (2006.01); A61P 7/02 (2006.01); A61P 7/04 (2006.01); A61P 7/06 (2006.01); A61P 9/00 (2006.01); A61P 9/04 (2006.01); A61P 9/06 (2006.01); A61P 9/10 (2006.01); A61P 9/12 (2006.01); A61P 11/00 (2006.01); A61P 11/06 (2006.01); A61P 13/12 (2006.01); A61P 17/00 (2006.01); A61P 17/02 (2006.01); A61P 17/06 (2006.01); A61P 17/14 (2006.01); A61P 19/02 (2006.01); A61P 19/10 (2006.01); A61P 21/00 (2006.01); A61P 25/00 (2006.01); A61P 25/16 (2006.01); A61P 25/28 (2006.01); A61P 27/02 (2006.01); A61P 27/06 (2006.01); A61P 31/04 (2006.01); A61P 31/06 (2006.01); A61P 31/16 (2006.01); A61P 31/22 (2006.01); A61P 33/10 (2006.01); A61P 35/00 (2006.01); A61P 37/02 (2006.01); A61P 37/06 (2006.01); A61P 37/08 (2006.01); C07K 14/715 (2006.01); C07K 16/30 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12P 21/02 (2006.01)
CPC (source: EP)
A61P 1/02 (2017.12); A61P 1/04 (2017.12); A61P 1/14 (2017.12); A61P 1/16 (2017.12); A61P 3/10 (2017.12); A61P 7/00 (2017.12); A61P 7/02 (2017.12); A61P 7/04 (2017.12); A61P 7/06 (2017.12); A61P 9/00 (2017.12); A61P 9/04 (2017.12); A61P 9/06 (2017.12); A61P 9/10 (2017.12); A61P 9/12 (2017.12); A61P 11/00 (2017.12); A61P 11/06 (2017.12); A61P 13/12 (2017.12); A61P 17/00 (2017.12); A61P 17/02 (2017.12); A61P 17/06 (2017.12); A61P 17/14 (2017.12); A61P 19/02 (2017.12); A61P 19/10 (2017.12); A61P 21/00 (2017.12); A61P 25/00 (2017.12); A61P 25/16 (2017.12); A61P 25/28 (2017.12); A61P 27/02 (2017.12); A61P 27/06 (2017.12); A61P 31/04 (2017.12); A61P 31/06 (2017.12); A61P 31/16 (2017.12); A61P 31/22 (2017.12); A61P 33/10 (2017.12); A61P 35/00 (2017.12); A61P 37/02 (2017.12); A61P 37/06 (2017.12); A61P 37/08 (2017.12); C07K 14/7151 (2013.01); A61K 38/00 (2013.01); Y02A 50/30 (2017.12)
Citation (search report)
- [X] LATZA UTE ET AL: "The human OX40 homolog: cDNA structure, expression and chromosomal assignment of the ACT35 antigen.", EUROPEAN JOURNAL OF IMMUNOLOGY, vol. 24, no. 3, p43489, 1994, pages 677 - 683, XP009003157, ISSN: 0014-2980 & DATABASE SWALL [online] 1 November 1995 (1995-11-01), "Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX-transcriptionally activated glycoprotein 1 receptor) (CD134 antigen)", XP002224396, Database accession no. p43489
- [XD] DATABASE SWALL [online] 1 June 1998 (1998-06-01), "Tumor necrosis factor receptor II homolog", XP002224397, Database accession no. O57116
- [X] NAISMITH J H ET AL: "Modularity in the TNF-receptor family", TIBS TRENDS IN BIOCHEMICAL SCIENCES, ELSEVIER PUBLICATION, CAMBRIDGE, EN, vol. 23, no. 2, 1 February 1998 (1998-02-01), pages 74 - 79, XP004108007, ISSN: 0968-0004
- See references of WO 0105834A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0105834 A1 20010125; WO 0105834 A9 20020718; AU 6102500 A 20010205; AU 780060 B2 20050224; CA 2381327 A1 20010125; EP 1203024 A1 20020508; EP 1203024 A4 20030226; JP 2003505045 A 20030212
DOCDB simple family (application)
US 0019343 W 20000714; AU 6102500 A 20000714; CA 2381327 A 20000714; EP 00947411 A 20000714; JP 2001511491 A 20000714