Global Patent Index - EP 1204766 A4

EP 1204766 A4 20030917 - SAMPLE ARRAYS AND HIGH-THROUGHPUT TESTING THEREOF TO DETECT INTERACTIONS

Title (en)

SAMPLE ARRAYS AND HIGH-THROUGHPUT TESTING THEREOF TO DETECT INTERACTIONS

Title (de)

PROBEN ARRAYS UND HOCHDURCHSATZTESTS DAMIT, UM WECHSELWIRKUNGEN NACHZUWEISEN

Title (fr)

RESEAUX D'ECHANTILLONS ET TEST A HAUT RENDEMENT DE CES DERNIERS POUR DETECTER DES INTERACTIONS

Publication

EP 1204766 A4 20030917 (EN)

Application

EP 00952298 A 20000728

Priority

  • US 0020717 W 20000728
  • US 14601999 P 19990728
  • US 54046200 A 20000331

Abstract (en)

[origin: WO0109391A1] The invention relates to high-throughput methods to prepare an array comprising a large number of samples, each sample consisting of a combination of components, at varying concentrations and identities, and high-throughput methods to test each sample for one or more properties. Such methods allow detection or measurement of interactions or detection of lack of interactions between inactive components and active components; between multiple inactive components; or between multiple active components. The invention is particularly suited for making a large number of pharmaceutical-excipient samples at the same time, then rapidly testing each sample to detect or measure an interaction. Once such interaction is detected or measured, it can be exploited to develop optimized formulations for pharmaceutical administration.

IPC 1-7

B01J 19/00; A61K 47/00; G01N 33/50

IPC 8 full level

G01N 33/15 (2006.01); B01J 19/00 (2006.01); G01N 37/00 (2006.01); C07B 61/00 (2006.01)

CPC (source: EP KR)

B01J 19/0046 (2013.01 - EP); C12Q 3/00 (2013.01 - KR); B01J 2219/00605 (2013.01 - EP); B01J 2219/0061 (2013.01 - EP); B01J 2219/00621 (2013.01 - EP); B01J 2219/0063 (2013.01 - EP); B01J 2219/00644 (2013.01 - EP); B01J 2219/00689 (2013.01 - EP); B01J 2219/00707 (2013.01 - EP); B01J 2219/0072 (2013.01 - EP); B01J 2219/00756 (2013.01 - EP); C40B 40/00 (2013.01 - EP)

Citation (search report)

  • [X] WO 9852614 A2 19981126 - UNIV LELAND STANFORD JUNIOR [US], et al
  • [X] WO 9852047 A1 19981119 - AURORA BIOSCIENCES CORP [US] & US 5985214 A 19991116 - STYLLI CHARI [US], et al
  • [EL] WO 0059627 A1 20001012 - MILLENNIUM PHARM INC [US]
  • [X] SONG C X ET AL: "Controlled release of U-86983 from double-layer biodegradable matrices: effect of additives on release mechanism and kinetics", JOURNAL OF CONTROLLED RELEASE,NL,ELSEVIER SCIENCE PUBLISHERS B.V. AMSTERDAM, vol. 45, no. 2, 17 March 1997 (1997-03-17), pages 177 - 192, XP004099366, ISSN: 0168-3659
  • [X] "1998 ARES meeting wine tasting", XP002248070
  • [XA] GOLD, G ET AL.: "Effects of Selected U.S.P. Talcs on Acetylsalicylic Acid Stability in Tablets", JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 53, no. 1, January 1964 (1964-01-01), pages 52 - 54, XP002144952
  • [X] WARD ET AL: "Automatic preparation of protein crystals using laboratory robotics and automated visual inspection", JOURNAL OF CRYSTAL GROWTH, NORTH-HOLLAND PUBLISHING CO. AMSTERDAM, NL, vol. 90, 1988, pages 325 - 339, XP002151642, ISSN: 0022-0248
  • See references of WO 0109391A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 0109391 A1 20010208; AU 6502300 A 20010219; BR 0012767 A 20020723; CA 2379160 A1 20010208; CZ 2002334 A3 20020612; EP 1204766 A1 20020515; EP 1204766 A4 20030917; IL 147646 A0 20020814; JP 2003509657 A 20030311; KR 20020034168 A 20020508; MX PA02000890 A 20031015; SK 1112002 A3 20020604

DOCDB simple family (application)

US 0020717 W 20000728; AU 6502300 A 20000728; BR 0012767 A 20000728; CA 2379160 A 20000728; CZ 2002334 A 20000728; EP 00952298 A 20000728; IL 14764600 A 20000728; JP 2001513646 A 20000728; KR 20027001169 A 20020128; MX PA02000890 A 20000728; SK 1112002 A 20000728