EP 1206278 A2 20020522 - PEPTIDE MIXTURE AND VACCINE AGAINST A CHRONIC VIRAL INFECTION
Title (en)
PEPTIDE MIXTURE AND VACCINE AGAINST A CHRONIC VIRAL INFECTION
Title (de)
PEPTIDGEMISCH UND IMPFSTOFF GEGEN EINE CHRONISCHE VIRALE INFEKTION
Title (fr)
MELANGE PEPTIDIQUE ET VACCIN CONTRE UNE INFECTION VIRALE CHRONIQUE
Publication
Application
Priority
- EP 0008124 W 20000821
- SE 9903031 A 19990827
Abstract (en)
[origin: WO0116163A2] Disclosed is a peptide mixture, a pharmaceutical composition and a vaccine against a chronic infection caused by a virus comprising a mixture of 10 to 30 amino acids (aa) long peptides each with a 5 to 25 aa overlap of the adjacent overlapping peptide spanning the amino acid sequence of a viral protein of said virus, e.g. Hepatitis B, Hepatitis C, GBvirus-C, HIV and Herpes viruses. Hepatitis B has been used as an example and it is demonstrated that a peptide mixture composed of seventeen 20 to 23 aa long peptides spanning the amino acids 1 to 183 of the hepatitis B core antigen (HBcAg) could activate specific T cells regardless of the host MHC/HLA genotype that recognize the native protein processed by professional antigen presenting cells (APCs). Further, a method is described for the treatment of a viral infection, particularly a non-resolving chronic viral infection, making use of the novel peptide mixture immunogen.
IPC 1-7
IPC 8 full level
A61K 38/00 (2006.01); A61K 39/00 (2006.01); A61K 39/12 (2006.01); A61K 39/245 (2006.01); A61K 39/29 (2006.01); A61P 31/12 (2006.01); A61P 31/18 (2006.01); A61P 31/22 (2006.01); C07K 7/08 (2006.01); C07K 14/02 (2006.01)
CPC (source: EP US)
A61P 31/12 (2018.01 - EP); A61P 31/18 (2018.01 - EP); A61P 31/22 (2018.01 - EP); C07K 14/005 (2013.01 - EP); A61K 38/00 (2013.01 - EP); A61K 39/00 (2013.01 - EP US); A61K 2039/57 (2013.01 - EP); C12N 2730/10122 (2013.01 - EP)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0116163 A2 20010308; WO 0116163 A3 20010907; AU 7903100 A 20010326; EP 1206278 A2 20020522; JP 2003508409 A 20030304; SE 9903031 D0 19990827
DOCDB simple family (application)
EP 0008124 W 20000821; AU 7903100 A 20000821; EP 00969241 A 20000821; JP 2001519724 A 20000821; SE 9903031 A 19990827