EP 1206315 A2 20020522 - ARRAYS COMPRISING A FIDUCIAL AND AUTOMATED INFORMATION PROCESSING IN RANDOMLY ORDERED ARRAYS
Title (en)
ARRAYS COMPRISING A FIDUCIAL AND AUTOMATED INFORMATION PROCESSING IN RANDOMLY ORDERED ARRAYS
Title (de)
MATRIZEN MIT BEZUGSMARKIERUNG UND AUTOMATISIERTER INFORMATIONSBEHANDLUNG MIT FREI WÄHLBAR ANGEORDNETEN MATRIZEN
Title (fr)
TRAITEMENT INFORMATISE D'INFORMATIONS DANS DES GROUPEMENTS ORDONNES DE MANIERE ALEATOIRE
Publication
Application
Priority
- US 0003375 W 20000209
- US 11932399 P 19990209
Abstract (en)
[origin: WO0047996A2] The invention relates to the use of a computer system to compare images generated from a randomly ordered array. This system preserves the relative position of each site within the array so that the same site can be compared in different images.
[origin: WO0047996A2] The present invention provides array compositions comprising a substrate with a surface comprising discrete sites, at least one fiducial, and a population of microspheres comprising at least a first and a second subpopulation, each comprising a bioactive agent, and distributed on said surface. Each subpopulation may optionally comprise a unique optical signature, an identifier binding ligand, or both. The invention further provides compositions comprising a computer readable memory, comprising data acquisition, registration, and comparison modules to direct a computer to function in a specified manner. The registration module may utilize any number of fiducials, including a fiducial fiber, a fiducial microsphere, or a fiducial template generated from the random array. In further aspects, the invention provided methods of making the array compositions of the invention, for comparing separate data images of a random array, for decoding a random array composition, and for determining the presence of a target analyte in a sample.
IPC 1-7
IPC 8 full level
G01N 33/53 (2006.01); B01J 19/00 (2006.01); G01N 21/64 (2006.01); G01N 21/77 (2006.01); G01N 21/78 (2006.01); G01N 33/566 (2006.01); G01N 37/00 (2006.01); C40B 70/00 (2006.01)
CPC (source: EP)
B01J 19/0046 (2013.01); G01N 21/6428 (2013.01); G01N 21/6456 (2013.01); G01N 21/7703 (2013.01); B01J 2219/00317 (2013.01); B01J 2219/005 (2013.01); B01J 2219/00572 (2013.01); B01J 2219/00585 (2013.01); B01J 2219/00596 (2013.01); B01J 2219/00648 (2013.01); B01J 2219/00659 (2013.01); B01J 2219/00689 (2013.01); B01J 2219/00704 (2013.01); B01J 2219/00707 (2013.01); B01J 2219/0072 (2013.01); C40B 70/00 (2013.01); G01N 21/553 (2013.01); G01N 21/6458 (2013.01); G01N 21/658 (2013.01); G01N 2021/6484 (2013.01)
Citation (search report)
See references of WO 0047996A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0047996 A2 20000817; WO 0047996 A3 20001221; WO 0047996 A9 20020411; AU 2004202799 A1 20040722; AU 3359400 A 20000829; AU 771458 B2 20040325; CA 2359352 A1 20000817; CA 2359352 C 20040921; EP 1206315 A2 20020522; JP 2002536665 A 20021029
DOCDB simple family (application)
US 0003375 W 20000209; AU 2004202799 A 20040623; AU 3359400 A 20000209; CA 2359352 A 20000209; EP 00911745 A 20000209; JP 2000598854 A 20000209