EP 1206454 A1 20020522 - NOVEL INTEGRIN ALPHAvBETA3 INHIBITORS
Title (en)
NOVEL INTEGRIN ALPHAvBETA3 INHIBITORS
Title (de)
NEUE INHIBITOREN DES INTEGRINS ALPHAvBETA3
Title (fr)
NOUVEAUX INHIBITEURS DE L'INTEGRINE ALPHAvBETA3
Publication
Application
Priority
- DE 19939981 A 19990824
- EP 0007591 W 20000804
Abstract (en)
[origin: DE19939981A1] The invention relates to novel compounds of formula (I) which are biologically active when present as ligands of the integrin alpha v beta 3: X-Y-Z-R<1>-CH2-R<2>(R<4>)-CH2-CO-R<5> wherein the meaning of X, Y, Z, R<1>, R<2>, R<4> and R<5> is given in Claim 1. The invention also relates to the physiologically acceptable salts and solvates of said compounds.
IPC 1-7
C07D 213/74; C07D 239/42; C07D 233/88; C07D 235/30; C07C 257/14; C07C 279/08; C07D 213/30; A61K 31/44; A61K 31/505; A61P 9/10
IPC 8 full level
A61K 31/4164 (2006.01); A61K 31/4168 (2006.01); A61K 31/4184 (2006.01); A61K 31/44 (2006.01); A61K 31/4402 (2006.01); A61P 7/02 (2006.01); A61P 9/10 (2006.01); A61P 17/02 (2006.01); A61P 17/06 (2006.01); A61P 19/10 (2006.01); A61P 29/00 (2006.01); C07D 233/64 (2006.01); A61P 31/00 (2006.01); A61P 35/00 (2006.01); C07D 213/74 (2006.01); C07D 233/48 (2006.01); C07D 233/88 (2006.01); C07D 235/30 (2006.01); C07D 239/42 (2006.01); C07D 521/00 (2006.01)
CPC (source: EP KR)
A61K 31/4402 (2013.01 - KR); A61P 7/02 (2018.01 - EP); A61P 9/10 (2018.01 - EP); A61P 17/02 (2018.01 - EP); A61P 17/06 (2018.01 - EP); A61P 19/10 (2018.01 - EP); A61P 29/00 (2018.01 - EP); A61P 31/00 (2018.01 - EP); A61P 35/00 (2018.01 - EP); C07D 213/74 (2013.01 - EP KR); C07D 231/12 (2013.01 - EP); C07D 233/48 (2013.01 - EP); C07D 233/56 (2013.01 - EP); C07D 233/88 (2013.01 - EP); C07D 235/30 (2013.01 - EP); C07D 239/42 (2013.01 - EP); C07D 249/08 (2013.01 - EP)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0114338 A1 20010301; AU 6570500 A 20010319; BR 0013504 A 20020507; CA 2382850 A1 20010301; CN 1370147 A 20020918; CZ 2002523 A3 20020515; DE 19939981 A1 20010301; EP 1206454 A1 20020522; HK 1049666 A1 20030523; HU P0203697 A2 20030328; HU P0203697 A3 20040428; JP 2003507458 A 20030225; KR 20020016651 A 20020304; MX PA02001861 A 20040906; NO 20020886 D0 20020222; NO 20020886 L 20020222; PL 352989 A1 20030922; SK 2282002 A3 20020604; ZA 200202287 B 20030827
DOCDB simple family (application)
EP 0007591 W 20000804; AU 6570500 A 20000804; BR 0013504 A 20000804; CA 2382850 A 20000804; CN 00811950 A 20000804; CZ 2002523 A 20000804; DE 19939981 A 19990824; EP 00953158 A 20000804; HK 03101785 A 20030312; HU P0203697 A 20000804; JP 2001518427 A 20000804; KR 20027001419 A 20020201; MX PA02001861 A 20000804; NO 20020886 A 20020222; PL 35298900 A 20000804; SK 2282002 A 20000804; ZA 200202287 A 20020320