EP 1206557 A2 20020522 - PLANT DEFENSIN VARIANTS
Title (en)
PLANT DEFENSIN VARIANTS
Title (de)
VARIANTEN VON DEFENSIN AUS PFLANZEN
Title (fr)
VARIANTES DE DEFENSIN DE PLANTES
Publication
Application
Priority
- GB 0002941 W 20000731
- GB 9918155 A 19990802
Abstract (en)
[origin: WO0109174A2] An antimicrobial protein or peptide derived from a plant defensin, or a derivative thereof, characterised in that said protein or peptide comprises one or more of the following replacement amino acid residues selected from the group consisting of: (i) a tryptophan residue at position 32; (ii) a valine, leucine, isoleucine, tryptophan, phenylalanine, lysine, arginine, tyrosine, methionine, cysteine or histidine residue at position 34; (iii) an isoleucine, tryptophan, lysine, arginine, valine, leucine, phenylalanine or histidine residue at position 35; (iv) a tryptophan residue at position 36; (v) a tryptophan, glycine, threonine, tyrosine, glutamine, lysine, arginine, phenylalanine or histidine residue at position 37; (vi) a leucine, isoleucine, tryptophan, phenylalanine, valine or cysteine residue at position 38; (vii) a leucine, isoleucine, tryptophan, phenylalanine, methionine, lysine, arginine, tyrosine or histidine residue at position 39; (viii) a tryptophan residue at position 40; (ix) an isoleucine, a tryptophan, phenylalanine, serine, threonine, tyrosine, glutamine, asparagine, lysine, arginine, histidine at position 41; and/or (x) a valine, leucine, isoleucine, tryptophan, phenylalanine, tyrosine, asparagine, lysine, arginine, serine or threonine residue at position 42; where said amino acid residues are not found naturally at said positions in the antimicrobial protein or peptide, with the proviso that the antimicrobial proteins do not comprise only a replacement arginine residue at position 37, 39 or 42. These proteins or peptides are useful in agriculture and pharmaceuticals.
IPC 1-7
IPC 8 full level
A01H 5/00 (2006.01); A01N 37/46 (2006.01); A01N 63/00 (2006.01); A01N 65/00 (2009.01); A61K 38/00 (2006.01); A61P 31/00 (2006.01); A61P 31/10 (2006.01); C07K 14/415 (2006.01); C12N 15/09 (2006.01); C12N 15/82 (2006.01)
CPC (source: EP)
A01N 65/00 (2013.01); A61P 31/00 (2017.12); A61P 31/10 (2017.12); C07K 14/415 (2013.01); C12N 15/8282 (2013.01)
Citation (search report)
See references of WO 0109174A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0109174 A2 20010208; WO 0109174 A3 20010830; AU 6579100 A 20010219; CA 2378432 A1 20010208; EP 1206557 A2 20020522; GB 9918155 D0 19991006; JP 2003507009 A 20030225
DOCDB simple family (application)
GB 0002941 W 20000731; AU 6579100 A 20000731; CA 2378432 A 20000731; EP 00953273 A 20000731; GB 9918155 A 19990802; JP 2001513980 A 20000731