EP 1206702 A1 20020522 - MELANOMA ASSOCIATED ANTIGEN (HMW-MAA) DEFINED BY A MONOCLONAL ANTIBODY
Title (en)
MELANOMA ASSOCIATED ANTIGEN (HMW-MAA) DEFINED BY A MONOCLONAL ANTIBODY
Title (de)
BESTIMMUNG DES MELANOMA ASSOZIIERTEN ANTIGENS (HMW-MAA) DURCH MONOKLONALE ANTIKÖRPER
Title (fr)
ANTIGENE ASSOCIE A UN MELANOME (HMW-MAA) DEFINI PAR UN ANTICORPS MONOCLONAL
Publication
Application
Priority
- SE 0001597 W 20000822
- SE 9902989 A 19990824
Abstract (en)
[origin: WO0114884A1] An epitope of high molecular weight melanoma associated antigen (HMW-MAA) displayed on the surface of human cells but not cells from Macaca fascicularis is described, said epitope a) having the ability of being specifically blocked by and specifically block a binding structure which recognizes HMW-MAA, b) being displayed on the surface of human cells but not cells from Macaca fascicularis, and c) having a normal tissue distribution pattern which is more restricted than that of other known epitopes of HMW-MAA. There is also described a binding structure and antibodies recognizing target structures of said antigen, pharmaceutical compositions and vaccines as well as methods of using said epitopes and antibodies in diagnostic and therapeutic methods related to human malignant diseases.
IPC 1-7
IPC 8 full level
A61K 39/00 (2006.01); C07K 16/30 (2006.01)
CPC (source: EP US)
A61K 39/00119 (2018.08 - EP US); C07K 16/3053 (2013.01 - EP); A61K 2039/505 (2013.01 - EP); C07K 2317/21 (2013.01 - EP); C07K 2317/55 (2013.01 - EP); C07K 2317/622 (2013.01 - EP); C07K 2319/00 (2013.01 - EP)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0114884 A1 20010301; AU 6883700 A 20010319; AU 762240 B2 20030619; CA 2381099 A1 20010301; EP 1206702 A1 20020522; NZ 517132 A 20031031; SE 9902989 D0 19990824
DOCDB simple family (application)
SE 0001597 W 20000822; AU 6883700 A 20000822; CA 2381099 A 20000822; EP 00957184 A 20000822; NZ 51713200 A 20000822; SE 9902989 A 19990824