EP 1207812 A4 20070620 - IMPLANT AND AGENT DELIVERY DEVICE
Title (en)
IMPLANT AND AGENT DELIVERY DEVICE
Title (de)
VORRICHTUNG ZUR FÜHRUNG EINER PROTHESE UND VERABREICHUNG EINES WIRKSTOFFS
Title (fr)
DISPOSITIF DE GUIDAGE D'IMPLANT ET D'ADMINISTRATION D'UN AGENT
Publication
Application
Priority
- US 0021215 W 20000803
- US 14709499 P 19990804
- US 14847599 P 19990812
Abstract (en)
[origin: WO0110350A1] The present invention provides a system (178) for delivering a therapeutic agent in combination with an implanted device (2) to maximize a therapeutic benefit offered by each. Preferably, the therapeutic agent is contained within a solid matrix form such as a pellet or gel to facilitate its handling, and to regulate its rate of dissipation into the tissue after delivery. The implant device (2) is specially configured to receive retain the matrix but permit blood to interact with the matrix so that the agent can be released to the blood in, around the device, and the surrounding tissue. A delivery system (178) comprises an implant delivery device having an obturator (180) capable of piercing the tissue and an agent matrix delivery device (210) to place a matrix form, such as a pellet, into the interior of the implant (2) after it has been implanted. Preferably, the implant delivery device (178) and the matrix delivery device (210) are contained in one apparatus to facilitate delivery of the pellet into the embedded implant. The present invention is useful for treating tissue in any area of the body, especially ischemic tissue experiencing reduced blood flow. The present devices and methods are especially useful for treatment of ischemia of the myocardium. In treatment of the myocardium, the present implant device and matrix combination may be delivered surgically through the epicardium of the heart.
IPC 1-7
IPC 8 full level
A61B 17/00 (2006.01); A61F 2/04 (2006.01); A61F 2/06 (2006.01); A61F 2/88 (2006.01); A61M 36/04 (2006.01); A61F 2/00 (2006.01); A61F 2/02 (2006.01)
CPC (source: EP)
A61F 2/2493 (2013.01); A61F 2/88 (2013.01); A61F 2250/0067 (2013.01)
Citation (search report)
- [XA] WO 9921510 A1 19990506 - KENSEY NASH CORP [US]
- [XA] WO 9732551 A1 19970912 - ENERGY LIFE SYSTEMS CORP [US]
- [X] WO 9816161 A1 19980423 - TRANSVASCULAR INC [US]
- [E] WO 0069504 A1 20001123 - BARD INC C R [US], et al
- [PX] WO 0018326 A1 20000406 - BARD INC C R [US]
- [A] WO 9922655 A1 19990514 - SCIMED LIFE SYSTEMS INC [US]
- [A] US 5487739 A 19960130 - AEBISCHER PATRICK [US], et al
- See references of WO 0110350A1
Designated contracting state (EPC)
DE ES FR GB IT
DOCDB simple family (publication)
WO 0110350 A1 20010215; EP 1207812 A1 20020529; EP 1207812 A4 20070620; JP 2003506143 A 20030218
DOCDB simple family (application)
US 0021215 W 20000803; EP 00953820 A 20000803; JP 2001514878 A 20000803