EP 1208088 A2 20020529 - FLUORENE DERIVATIVES AS INTEGRIN INHIBITORS
Title (en)
FLUORENE DERIVATIVES AS INTEGRIN INHIBITORS
Title (de)
FLUORENDERIVATE ALS INTEGRININHIBITOREN
Title (fr)
DERIVES DE FLUORENE COMME INHIBITEURS D'INTEGRINE
Publication
Application
Priority
- DE 19937394 A 19990807
- EP 0007153 W 20000726
Abstract (en)
[origin: DE19937394A1] The invention relates to compounds of formula (I) wherein R<1>, R<2>, R<3>, R<4>, R<5>, m and n have the meaning given in Claim 1, and to their physiologically acceptable salts and solvates, which can be used as integrin inhibitors, especially for the prophylaxis and treatment of blood circulation disorders, thrombosis, myocardial infarction, coronary disorders, arteriosclerosis, osteoporosis, pathological processes which are maintained or propagated through angiogenesis, as well as in tumour therapy.
IPC 1-7
C07D 233/48; C07D 235/30; A61K 31/4168; A61K 31/4184; A61P 7/02; A61P 9/10
IPC 8 full level
A61K 31/4164 (2006.01); A61K 31/4184 (2006.01); A61P 7/02 (2006.01); A61P 9/04 (2006.01); A61P 9/10 (2006.01); A61P 19/02 (2006.01); A61P 19/10 (2006.01); A61P 35/00 (2006.01); C07C 279/12 (2006.01); C07D 233/48 (2006.01); C07D 235/30 (2006.01)
CPC (source: EP)
A61P 7/00 (2018.01); A61P 7/02 (2018.01); A61P 9/00 (2018.01); A61P 9/04 (2018.01); A61P 9/10 (2018.01); A61P 19/02 (2018.01); A61P 19/10 (2018.01); A61P 35/00 (2018.01); C07C 279/12 (2013.01); C07D 233/48 (2013.01); C07C 2603/10 (2017.05)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0110841 A2 20010215; WO 0110841 A3 20010907; AR 025042 A1 20021106; AU 6828600 A 20010305; BR 0013083 A 20020423; CA 2380981 A1 20010215; CN 1368962 A 20020911; CZ 2002298 A3 20020417; DE 19937394 A1 20010208; EP 1208088 A2 20020529; HK 1049006 A1 20030425; HU P0202464 A2 20021228; HU P0202464 A3 20030228; JP 2003506439 A 20030218; KR 20020012631 A 20020216; MX PA02001297 A 20040716; NO 20020592 D0 20020206; NO 20020592 L 20020404; PL 353054 A1 20031006; SK 1402002 A3 20020604; ZA 200201873 B 20030827
DOCDB simple family (application)
EP 0007153 W 20000726; AR P000104035 A 20000804; AU 6828600 A 20000726; BR 0013083 A 20000726; CA 2380981 A 20000726; CN 00811476 A 20000726; CZ 2002298 A 20000726; DE 19937394 A 19990807; EP 00956284 A 20000726; HK 03101305 A 20030220; HU P0202464 A 20000726; JP 2001515308 A 20000726; KR 20027000660 A 20020116; MX PA02001297 A 20000726; NO 20020592 A 20020206; PL 35305400 A 20000726; SK 1402002 A 20000726; ZA 200201873 A 20020306