EP 1208114 A2 20020529 - INDUCTION OF PROGRAMMED CELL DEATH BY N5 GENE
Title (en)
INDUCTION OF PROGRAMMED CELL DEATH BY N5 GENE
Title (de)
INDUKTION DER PROGRAMMIERTEN ZELLTOD DURCH DAS N5 GENE
Title (fr)
INDUCTION DE LA MORT CELLULAIRE PROGRAMMEE PAR LE GENE N5
Publication
Application
Priority
- US 0024075 W 20000831
- US 15168799 P 19990831
Abstract (en)
[origin: WO0116168A2] The present invention concerns methods and compositions for treating cancer in a subject. These methods and compositions utilize the activities associated with the N5 gene product, p84N5. p84N5 contains a functional death domain, can interact with the retinoblastoma gene product and is normally localized to the nucleus of cells. Increasing the activity level of p84N5 in cancer cells is beneficial for the treatment of cancer.
IPC 1-7
C07K 14/47; C12N 15/12; C12N 5/10; C12N 15/86; C12N 15/861; C12N 15/869; C12N 15/867
IPC 8 full level
C07K 14/47 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01)
CPC (source: EP)
C07K 14/47 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01); C07K 2319/00 (2013.01); C12N 2799/021 (2013.01); C12N 2799/022 (2013.01)
Citation (search report)
See references of WO 0116168A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0116168 A2 20010308; WO 0116168 A3 20010614; WO 0116168 A9 20020912; AU 7102400 A 20010326; CA 2382952 A1 20010308; EP 1208114 A2 20020529
DOCDB simple family (application)
US 0024075 W 20000831; AU 7102400 A 20000831; CA 2382952 A 20000831; EP 00959759 A 20000831