EP 1208212 A1 20020529 - FIBRIN SEALANT AS A TRANSFECTION/TRANSFORMATION VEHICLE FOR GENE THERAPY
Title (en)
FIBRIN SEALANT AS A TRANSFECTION/TRANSFORMATION VEHICLE FOR GENE THERAPY
Title (de)
FIBRINKLEBER ALS TRANSFEKTIONS-/TRANSFORMATIONS-VEHIKEL ZUR GENTHERAPIE
Title (fr)
MATERIAU D'OBTURATION A BASE DE FIBRINE UTILISE COMME VEHICULE DE TRANSFECTION/TRANSFORMATION DESTINE A LA THERAPIE GENIQUE
Publication
Application
Priority
US 9913508 W 19990616
Abstract (en)
[origin: WO0077227A1] Provided, for example, is a method of transforming a cell comprising the steps of: applying a transformation effective amount of a nucleic acid to the cell; applying a fibrin gel to the cell so as to entrap a transformation effective amount of the nucleic acid; and transforming the cell with the nucleic acid. In one aspect, the nucleic acid is applied in admixture with a fibrin or fibrinogen composition that forms the fibrin gel.
IPC 1-7
IPC 8 full level
A61K 48/00 (2006.01); C12N 15/09 (2006.01); A61K 9/06 (2006.01); A61K 39/00 (2006.01); A61K 39/39 (2006.01); A61K 39/395 (2006.01); A61K 47/42 (2006.01); A61L 24/10 (2006.01); C07K 14/745 (2006.01); A61K 35/12 (2015.01)
CPC (source: EP)
A61K 47/42 (2013.01); A61K 48/00 (2013.01); A61L 24/106 (2013.01); C07K 14/745 (2013.01); A61K 35/12 (2013.01); A61K 2039/53 (2013.01); Y02A 50/30 (2017.12)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0077227 A1 20001221; CA 2375346 A1 20001221; EP 1208212 A1 20020529; EP 1208212 A4 20070502; JP 2003502047 A 20030121
DOCDB simple family (application)
US 9913508 W 19990616; CA 2375346 A 19990616; EP 99935322 A 19990616; JP 2001503669 A 19990616