EP 1212096 A2 20020612 - DRUG CONJUGATES AND METHODS OF DESIGNING THE SAME
Title (en)
DRUG CONJUGATES AND METHODS OF DESIGNING THE SAME
Title (de)
ARZNEIMITTELKONJUGATE UND VERFAHREN ZUR HERSTELLUNG
Title (fr)
CONJUGUES DE MEDICAMENTS ET LEURS PROCEDES DE PREPARATION
Publication
Application
Priority
- US 0023593 W 20000828
- US 15076599 P 19990826
- US 15089499 P 19990826
- US 18441100 P 20000223
- US 18441200 P 20000223
Abstract (en)
[origin: WO0113958A2] The invention relates to drug conjugates and methods of their design. One embodiment of the invention is directed to a method of designing vector-linker-pharmacophore ("VLP") conjugates that is generally applicable to a wide variety of vectors, linkers, and pharmacophores. The invention also encompasses a method of improving the delivery of a pharmacophore to a patient, as well as a method of improving the therapeutic efficacy of a pharmacophore and a method of decreasing the toxicity of a pharmacophore. A method of increasing the concentration of a pharmacophore in a cell is further encompassed by the invention.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); A61K 47/34 (2006.01); A61K 47/48 (2006.01); C40B 40/02 (2006.01); C40B 50/06 (2006.01)
CPC (source: EP)
A61K 47/54 (2017.07)
Citation (search report)
See references of WO 0113958A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0113958 A2 20010301; WO 0113958 A3 20020131; AU 7082400 A 20010319; CA 2382202 A1 20010301; EP 1212096 A2 20020612; JP 2003507439 A 20030225
DOCDB simple family (application)
US 0023593 W 20000828; AU 7082400 A 20000828; CA 2382202 A 20000828; EP 00959512 A 20000828; JP 2001518093 A 20000828