EP 1212433 A2 20020612 - PROTEIN PHOSPHATASES AND DIAGNOSIS AND TREATMENT OF PHOSPHATASE-RELATED DISORDERS
Title (en)
PROTEIN PHOSPHATASES AND DIAGNOSIS AND TREATMENT OF PHOSPHATASE-RELATED DISORDERS
Title (de)
PROTEINPHOSPHATASEN SOWIE DIAGNOSE UND BEHANDLUNG VON PHOSPHATASE BEDINGTEN BESCHWERDEN
Title (fr)
NOUVELLES PHOSPHATASES DE PROTEINES ET DIAGNOSTIC ET TRAITEMENT DES TROUBLES LIES A LA PHOSPHATASE
Publication
Application
Priority
- US 0022158 W 20000811
- US 14900599 P 19990813
Abstract (en)
[origin: WO0112819A2] The present invention concerns polypeptides, nucleic acids encoding such polypeptides, cells, tissues and animals containing such nucleic acids, antibodies to the polypeptides, assays utilizing the polypeptides, and methods relating to all of the foregoing. Preferably, the polypeptides of the present invention are phosphatases. Through the use of a "motif extraction" bioinformatics script, additional mammalian members of the phosphatase family are herein presented. These phosphatases include MKP-like proteins, a CDC14-like protein, a PTEN-like protein, and myotubularin (MTM)-like proteins. Classification of proteins as new members of established families has proven highly accurate not only in predicting motifs present in the remaining non-catalytic portion of each protein, but also in their regulation, substrates, and signaling pathways.
IPC 1-7
C12N 15/55; C12N 9/16; C07K 16/40; C12Q 1/42; C12Q 1/68; A61K 38/46
IPC 8 full level
G01N 33/50 (2006.01); A61K 38/46 (2006.01); A61K 45/00 (2006.01); A61P 1/00 (2006.01); A61P 1/16 (2006.01); A61P 7/00 (2006.01); A61P 9/00 (2006.01); A61P 9/04 (2006.01); A61P 11/00 (2006.01); A61P 13/00 (2006.01); A61P 13/12 (2006.01); A61P 15/00 (2006.01); A61P 17/00 (2006.01); A61P 21/00 (2006.01); A61P 25/00 (2006.01); A61P 25/18 (2006.01); A61P 27/02 (2006.01); A61P 35/00 (2006.01); C07K 16/40 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 9/16 (2006.01); C12N 15/02 (2006.01); C12N 15/09 (2006.01); C12N 15/55 (2006.01); C12Q 1/02 (2006.01); C12Q 1/42 (2006.01); C12Q 1/68 (2006.01); C12Q 1/6883 (2018.01); C12Q 1/6886 (2018.01); G01N 33/15 (2006.01); G01N 33/53 (2006.01); G01N 33/566 (2006.01)
CPC (source: EP)
A61P 1/00 (2017.12); A61P 1/16 (2017.12); A61P 7/00 (2017.12); A61P 9/00 (2017.12); A61P 9/04 (2017.12); A61P 11/00 (2017.12); A61P 13/00 (2017.12); A61P 13/12 (2017.12); A61P 15/00 (2017.12); A61P 17/00 (2017.12); A61P 21/00 (2017.12); A61P 25/00 (2017.12); A61P 25/18 (2017.12); A61P 27/02 (2017.12); A61P 35/00 (2017.12); C12N 5/10 (2013.01); C12N 9/16 (2013.01); C12Q 1/42 (2013.01); C12Q 1/6883 (2013.01); C12Q 1/6886 (2013.01); C12Y 301/03016 (2013.01); C12Y 301/03048 (2013.01); G01N 33/6893 (2013.01); A61K 2039/505 (2013.01); G01N 2500/02 (2013.01)
Citation (search report)
See references of WO 0112819A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0112819 A2 20010222; WO 0112819 A3 20020124; AU 6903800 A 20010313; CA 2377662 A1 20010222; EP 1212433 A2 20020612; JP 2003507016 A 20030225
DOCDB simple family (application)
US 0022158 W 20000811; AU 6903800 A 20000811; CA 2377662 A 20000811; EP 00957413 A 20000811; JP 2001516906 A 20000811