EP 1214361 A1 20020619 - TEMPERATURE SENSITIVE POLYMERS
Title (en)
TEMPERATURE SENSITIVE POLYMERS
Title (de)
TEMPERATUREMPFINDLICHE POLYMERE
Title (fr)
POLYMERES SENSIBLES A LA TEMPERATURE
Publication
Application
Priority
- EP 00950086 A 20000728
- EP 99202523 A 19990730
- NL 0000542 W 20000728
Abstract (en)
[origin: EP1072617A1] The present invention relates to compositions comprising polymers whose solubility characteristics can be changed by incubation. Another aspect of this invention is the application of such temperature sensitive polymers as release systems of biologically active compounds. The polymers of the present invention, comprise monomers which have modifiable functionality. The functionality of the monomers can for example be modified by the presence of hydrolysable groups. The modification is effected by the incubation, leading to a change of the water solubility characteristics of the polymer. The polymers used in the present invention contain hydrolysable chemical groups. As a result the polymer's solution characteristics, specifically its lower critical solution temperature (LCST), change upon incubation.
IPC 1-7
IPC 8 full level
A61K 9/14 (2006.01); A61K 47/32 (2006.01); C08F 8/12 (2006.01); C08F 20/10 (2006.01); C08F 20/54 (2006.01); C08F 220/28 (2006.01); C08F 220/54 (2006.01)
CPC (source: EP US)
C08F 8/44 (2013.01 - EP); C08F 220/54 (2013.01 - EP US); C08F 220/20 (2013.01 - EP)
Citation (search report)
See references of WO 0109198A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
EP 1072617 A1 20010131; AU 6323600 A 20010219; EP 1214361 A1 20020619; JP 2003506497 A 20030218; WO 0109198 A1 20010208
DOCDB simple family (application)
EP 99202523 A 19990730; AU 6323600 A 20000728; EP 00950086 A 20000728; JP 2001514004 A 20000728; NL 0000542 W 20000728