EP 1214454 A1 20020619 - HEPATITIS C VIRUS REPLICATION INHIBITORS
Title (en)
HEPATITIS C VIRUS REPLICATION INHIBITORS
Title (de)
INHIBITOREN DER HEPATITIS C VIRUS REPLIKATION
Title (fr)
INHIBITEURS DE REPLICATION DU VIRUS DE L'HEPATITE C
Publication
Application
Priority
- US 0023444 W 20000825
- US 15139599 P 19990830
Abstract (en)
[origin: WO0116379A1] The present application identifies the NS4A binding site present on NS2/3 as a target site for inhibiting NS2/3 protease activity. Methods inhibiting NS2/3 activity by targeting the identified target site are described along with examples of compounds useful in such methods and guidance for obtaining additional useful compounds. Such compounds and methods are preferably employed to inhibit HCV replication.
IPC 1-7
IPC 8 full level
A61K 38/16 (2006.01); C07K 14/18 (2006.01); G01N 33/576 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01)
CPC (source: EP)
A61K 38/162 (2013.01); C07K 14/005 (2013.01); G01N 33/5767 (2013.01); A61K 48/00 (2013.01); C12N 2770/24222 (2013.01)
Citation (search report)
See references of WO 0116379A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0116379 A1 20010308; CA 2383411 A1 20010308; EP 1214454 A1 20020619
DOCDB simple family (application)
US 0023444 W 20000825; CA 2383411 A 20000825; EP 00957832 A 20000825