EP 1216234 B1 20041229 - MEDIATORS OF HEDGEHOG SIGNALING PATHWAYS, COMPOSITIONS AND USES RELATED THERETO
Title (en)
MEDIATORS OF HEDGEHOG SIGNALING PATHWAYS, COMPOSITIONS AND USES RELATED THERETO
Title (de)
VERMITTLER VON IGEL SIGNALWEGEN, DEREN ZUSAMMENSTELLUNGEN UND VERWENDUNGEN
Title (fr)
MEDIATEURS DE VOIES DE SIGNALISATION HEDGEHOG, PREPARATIONS ET UTILISATIONS ASSOCIEES
Publication
Application
Priority
- US 0025461 W 20000915
- US 15452699 P 19990916
- US 15941299 P 19991014
- US 16289999 P 19991101
Abstract (en)
[origin: WO0119800A2] The present invention makes available methods and reagents for inhibiting aberrant growth states resulting from <i>hedgehog</i> gain-of-function by contacting the cell with a <i>hedgehog</i> antagonist, such as a small molecule, in a sufficient amount to aberrant growth state, e.g., to agonize a normal <i>ptc</i> pathway or antagonize <i>hedgehog</i> activity.
IPC 1-7
C07D 239/91; C07D 239/36; C07D 471/04; C07D 401/12; A61K 31/505; A61P 35/00; A61K 7/48; A61K 7/06
IPC 8 full level
A61K 31/165 (2006.01); A61K 31/166 (2006.01); A61K 31/505 (2006.01); A61K 31/517 (2006.01); A61P 1/02 (2006.01); A61P 1/16 (2006.01); A61P 1/18 (2006.01); A61P 17/00 (2006.01); A61P 17/02 (2006.01); A61P 17/06 (2006.01); A61P 17/14 (2006.01); A61P 19/00 (2006.01); A61P 19/02 (2006.01); A61P 27/02 (2006.01); A61P 27/12 (2006.01); A61P 35/00 (2006.01); A61P 37/08 (2006.01); C07D 239/00 (2006.01); C07D 239/36 (2006.01); C07D 239/91 (2006.01); C07D 401/12 (2006.01); C07D 403/06 (2006.01); C07D 405/12 (2006.01); C07D 471/04 (2006.01); C12N 5/07 (2010.01); C12N 5/071 (2010.01)
CPC (source: EP US)
A61P 1/02 (2017.12 - EP); A61P 1/16 (2017.12 - EP); A61P 1/18 (2017.12 - EP); A61P 17/00 (2017.12 - EP); A61P 17/02 (2017.12 - EP); A61P 17/06 (2017.12 - EP); A61P 17/14 (2017.12 - EP); A61P 19/00 (2017.12 - EP); A61P 19/02 (2017.12 - EP); A61P 27/02 (2017.12 - EP); A61P 27/12 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 37/08 (2017.12 - EP); C07D 239/36 (2013.01 - EP US); C07D 239/91 (2013.01 - EP US); C07D 401/12 (2013.01 - EP US); C07D 471/04 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0119800 A2 20010322; WO 0119800 A3 20011206; WO 0119800 A9 20021003; AT E286033 T1 20050115; AU 2005220214 A1 20051103; AU 2009203002 A1 20090813; AU 7494800 A 20010417; AU 780846 B2 20050421; AU 780846 C 20010417; CA 2385736 A1 20010322; CA 2385736 C 20111115; DE 60017157 D1 20050203; DE 60017157 T2 20051222; EP 1216234 A2 20020626; EP 1216234 B1 20041229; EP 1516876 A1 20050323; ES 2234662 T3 20050701; JP 2003509414 A 20030311; JP 4994552 B2 20120808; US 6545005 B1 20030408
DOCDB simple family (application)
US 0025461 W 20000915; AT 00963551 T 20000915; AU 2005220214 A 20051006; AU 2009203002 A 20090723; AU 7494800 A 20000915; CA 2385736 A 20000915; DE 60017157 T 20000915; EP 00963551 A 20000915; EP 04028252 A 20000915; ES 00963551 T 20000915; JP 2001523380 A 20000915; US 66383500 A 20000915