EP 1218521 A1 20020703 - USE OF SOLUBLE COSTIMULATORY FACTOR FOR TUMOR IMMUNO-GENE THERAPY
Title (en)
USE OF SOLUBLE COSTIMULATORY FACTOR FOR TUMOR IMMUNO-GENE THERAPY
Title (de)
VERWENDUNG VON LÖSLICHEN KOSTIMULATORISCHEN FAKTOREN FÜR DIE TUMOR-IMMUN-GENTHERAPY
Title (fr)
UTILISATION DE FACTEUR SOLUBLE CO-STIMULANT POUR THERAPIE IMMUNOGENE DE TUMEUR
Publication
Application
Priority
- US 0027405 W 20001005
- US 15778799 P 19991005
Abstract (en)
[origin: WO0125450A1] A new gene therapy entails tumor treatment by introducing an expressible nucleotide sequence for a soluble costimulatory factor, thereby enhancing the response of T-cells to a tumor. <i>In vivo</i> expression of the soluble factor overcomes anergy or tolerance to tumor cells and activates T-cells that are infiltrating or surrounding the tumor. A pharmaceutical composition containing such a gene is effective in tumor suppression.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); A61K 35/76 (2006.01); A61K 38/00 (2006.01); A61K 38/17 (2006.01); A61K 48/00 (2006.01); A61P 35/00 (2006.01); A61P 37/04 (2006.01); A61P 43/00 (2006.01); C07K 14/705 (2006.01)
CPC (source: EP)
A61P 35/00 (2017.12); A61P 37/04 (2017.12); A61P 43/00 (2017.12); C07K 14/70532 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01); C07K 2319/00 (2013.01)
Citation (search report)
See references of WO 0125450A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0125450 A1 20010412; AU 7856800 A 20010510; CA 2386533 A1 20010412; EP 1218521 A1 20020703; JP 2003511394 A 20030325
DOCDB simple family (application)
US 0027405 W 20001005; AU 7856800 A 20001005; CA 2386533 A 20001005; EP 00968693 A 20001005; JP 2001528602 A 20001005