Global Patent Index - EP 1218753 A2

EP 1218753 A2 20020703 - THROMBOTIC EPISODE RISK ASSAYS USING OXIDIZED PHOSPHOLIPIDS

Title (en)

THROMBOTIC EPISODE RISK ASSAYS USING OXIDIZED PHOSPHOLIPIDS

Title (de)

THROMBOSENEPISODENRISIKO-BESTIMMUNGEN UNTER VERWENDUNG VON OXIDIERTEN PHOSPHOLIPIDEN

Title (fr)

ESSAIS RELATIFS A L'EVALUATION DE RISQUE D'EPISODE THROMBOTIQUE REPOSANT SUR L'UTILISATION DE PHOSPHOLIPIDES OXYDES

Publication

EP 1218753 A2 20020703 (EN)

Application

EP 00965455 A 20000926

Priority

  • US 0026438 W 20000926
  • US 15656499 P 19990928

Abstract (en)

[origin: WO0123895A2] An assay to assess thrombotic risk in which oxidized lipids comprising phospholipids are utilized as a membrane source in a clotting assay and the results compared to an assay in which unoxidized phospholipid is used as a membrane source in the presence and absence of activated protein C ("APC"). The assay can monitor for the presence of antibodies in the patient which interfere specifically with the anticoagulant function of APC in an oxidation dependent or independent manner. This can indicate the propensity of the patient to experience episodes of vein thrombosis or arterial thrombosis.

IPC 1-7

G01N 33/86

IPC 8 full level

G01N 33/49 (2006.01); G01N 33/53 (2006.01); G01N 33/566 (2006.01); G01N 33/86 (2006.01)

CPC (source: EP)

G01N 33/86 (2013.01); G01N 2405/04 (2013.01)

Citation (search report)

See references of WO 0123895A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 0123895 A2 20010405; WO 0123895 A3 20010607; AU 7617300 A 20010430; AU 772269 B2 20040422; CA 2385012 A1 20010405; EP 1218753 A2 20020703; JP 2003510610 A 20030318

DOCDB simple family (application)

US 0026438 W 20000926; AU 7617300 A 20000926; CA 2385012 A 20000926; EP 00965455 A 20000926; JP 2001527230 A 20000926