Title (en)

RESONANT OPTICAL CAVITIES FOR HIGH-SENSITIVITY, HIGH-THROUGHPUT BIOLOGICAL SENSORS AND METHODS

Title (de)

RESONIERENDE OPTISCHE KAVITÄTEN FÜR HOCHSENSITIVE HOCHDURCHSATZ-BIOSENSOREN UND ENTSPRECHENDE VERFAHREN

Title (fr)

CAVITES OPTIQUES RESONNANTES DESTINEES A DES BIODETECTEURS A GRANDE SENSIBILITE ET A HAUT RENDEMENT ET PROCEDES UTILISANT CES BIODETECTEURS

Publication

EP 1221051 A2 20020710 (EN)

Application

EP 00992472 A 20001012

Priority

• US 0041138 W 20001012
• US 15936699 P 19991014

Abstract (en)

[origin: WO0140757A2] Biosensors including resonant optical cavities. The resonant optical cavities are shaped so as to generate whispering gallery modes, which increase the quality factors of the cavities and facilitate the detection of analytes in a sample with enhanced sensitivity. The sizes of the resonant optical cavities facilitate their use in biosensors that include arrays of sensing zones. Accordingly, the resonant optical cavities may be used in high-density sensing arrays that can be read in real-time and in parallel. Thus, the resonant optical cavities are useful for detecting small concentrations of samples in real-time and with high throughput. Different embodiments of the biosensors are also disclosed, as are methods for using the biosensors.

IPC 1-7

G01N 33/543

IPC 8 full level

G01N 21/25 (2006.01); G01N 21/27 (2006.01); G01N 21/55 (2006.01); G01N 21/64 (2006.01); G01N 33/543 (2006.01); G01N 33/566 (2006.01); G01N 37/00 (2006.01)

CPC (source: EP)

B82Y 30/00 (2013.01); G01N 21/6428 (2013.01); G01N 21/6452 (2013.01); G01N 21/648 (2013.01); G01N 21/7746 (2013.01)

Designated contracting state (EPC)

DE FR GB IT

DOCDB simple family (publication)

WO 0140757 A2 20010607; WO 0140757 A3 20020314; AU 4503201 A 20010612; CA 2384977 A1 20010607; EP 1221051 A2 20020710; EP 1221051 A4 20030305; JP 2003515737 A 20030507

DOCDB simple family (application)

US 0041138 W 20001012; AU 4503201 A 20001012; CA 2384977 A 20001012; EP 00992472 A 20001012; JP 2001542173 A 20001012