EP 1221963 A1 20020717 - COMPOUNDS FOR INHIBITION OF OSTEOCLASTOGENESIS
Title (en)
COMPOUNDS FOR INHIBITION OF OSTEOCLASTOGENESIS
Title (de)
VERBINDUNGEN ZUR HEMMUNG DER OSTEOCLASTOGENESE
Title (fr)
COMPOSÉS POUR L'INHIBITION DE L'OSTÉOCLASTOGENÈSE
Publication
Application
Priority
- US 0020510 W 20000728
- US 14609099 P 19990728
Abstract (en)
[origin: WO0108699A1] Methods of inhibiting osteoclastogenesis and the activity of osteoclasts are disclosed. Methods of treating patients who have diseases characterized bone loss are disclosed. The present invention also provides peptides and peptide analogues designed from a binding loop of a member of the tumor necrosis factor receptor (TNF-R) superfamily. According to the methods, an amount of an inhibitor effective to inhibit osteoclastogenesis is administered to the patient. Methods of modulating dendritic cell maturation, T cell proliferation, and/or CD40 receptor systems in an individual are disclosed. The methods comprise the step of administering to the individual an amount of an inhibitor effective to modulating dendriticall maturation, T cell proliferation, and/or CD40 receptor systems.
IPC 1-7
IPC 8 full level
A61K 38/00 (2006.01); A61K 38/12 (2006.01); A61K 38/16 (2006.01); A61K 38/17 (2006.01); A61K 45/00 (2006.01); A61P 1/02 (2006.01); A61P 19/02 (2006.01); A61P 19/08 (2006.01); A61P 19/10 (2006.01); A61P 29/00 (2006.01); A61P 43/00 (2006.01); C12N 15/09 (2006.01)
CPC (source: EP)
A61K 38/177 (2013.01); A61P 1/02 (2017.12); A61P 19/02 (2017.12); A61P 19/08 (2017.12); A61P 19/10 (2017.12); A61P 29/00 (2017.12); A61P 43/00 (2017.12)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0108699 A1 20010208; AU 6611100 A 20010219; AU 777634 B2 20041028; CA 2380009 A1 20010208; EP 1221963 A1 20020717; EP 1221963 A4 20060322; JP 2003505514 A 20030212
DOCDB simple family (application)
US 0020510 W 20000728; AU 6611100 A 20000728; CA 2380009 A 20000728; EP 00953710 A 20000728; JP 2001513429 A 20000728