EP 1223984 A2 20020724 - COMPOUNDS THAT ASSOCIATE ON THE INTERMOLECULAR LEVEL AND AGGREGATE BODIES THAT CONTAIN THEM
Title (en)
COMPOUNDS THAT ASSOCIATE ON THE INTERMOLECULAR LEVEL AND AGGREGATE BODIES THAT CONTAIN THEM
Title (de)
INTERMOLEKULAR ASSOZIIERENDE VERBINDUNGEN UND DIESE UMFASSENDE AGGREGATE
Title (fr)
COMPOSES A ASSOCIATION INTERMOLECULAIRE ET AGREGATS ENGLOBANT CES COMPOSES
Publication
Application
Priority
- DE 19930177 A 19990630
- EP 0006139 W 20000630
Abstract (en)
[origin: DE19930177A1] The invention relates to a compound of the general formula (I) X(B)m, wherein X is a unit of the value m and the members B are the same or different and represent K-R, wherein K represents a bond or A<1>-(A<2>-A<3>)k-sp, wherein A<1> is (CH2)tY(CH2)u, wherein Y is >C=0, >NH, -O-, -S- or a bond, t is an integer from 0 to 6 and u is an integer from 0 to 6, A<2> represents -NHCO-, -CONH-, -OCONH- or SCONH-, or -CO-, A<3> is (CH2)r, O(CH2)r, NH(CH2)r, S(CH2)r, or -(CHQ)-, wherein r is an integer from 1 to 6 and Q is a substituted or unsubstituted alkyl or aryl group, sp represents a bivalent spacer or a bond, and k is an integer from 5 to 100, and R represents hydrogen, a ligand that is suitable to specifically bind to a receptor, a marker molecule or a catalytically active group, and m is at least 2, with the proviso that (1) in the compound at least one R is different from hydrogen, (2) at least 2 K are present that do not represent a bond, and (3) X, the members B and m are selected in such a manner that K can be associated on the intermolecular level in the liquid phase by the formation of hydrogen bonds and the simultaneous formation of aggregate bodies that represent on their surfaces several R that are different from hydrogen, and (4) the molar mass of fragment X(K)m is less than 20.000.
IPC 1-7
IPC 8 full level
A61K 31/7008 (2006.01); A61K 39/395 (2006.01); A61K 47/42 (2006.01); A61K 47/48 (2006.01); A61P 29/00 (2006.01); A61P 31/04 (2006.01); A61P 31/12 (2006.01); A61P 35/00 (2006.01); A61P 37/00 (2006.01); A61P 43/00 (2006.01); C07H 13/04 (2006.01); C07H 15/04 (2006.01); C07H 15/18 (2006.01); C07K 5/00 (2006.01); C07K 7/06 (2006.01); C07K 9/00 (2006.01); G01N 33/531 (2006.01)
CPC (source: EP US)
A61K 47/54 (2017.08 - EP US); A61K 47/6929 (2017.08 - EP US); A61P 29/00 (2018.01 - EP); A61P 31/04 (2018.01 - EP); A61P 31/12 (2018.01 - EP); A61P 35/00 (2018.01 - EP); A61P 37/00 (2018.01 - EP); A61P 43/00 (2018.01 - EP); C07H 13/04 (2013.01 - EP US); C07H 15/04 (2013.01 - EP US); C07H 15/18 (2013.01 - EP US); C07K 7/06 (2013.01 - EP US); C07K 9/001 (2013.01 - EP US); G01N 33/531 (2013.01 - EP US)
Citation (examination)
"Biochemical organic compounds for research and diagnostic agents", 1991, SIGMA CHEMICAL COMPANY, article "POLYGLYCINE", pages: 1717
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
DE 19930177 A1 20010111; DE 19930177 B4 20070208; AU 6266900 A 20010122; CA 2376164 A1 20010111; CA 2376164 C 20110816; EP 1223984 A2 20020724; JP 2003503465 A 20030128; US 7294615 B1 20071113; WO 0102018 A2 20010111; WO 0102018 A3 20020314
DOCDB simple family (application)
DE 19930177 A 19990630; AU 6266900 A 20000630; CA 2376164 A 20000630; EP 0006139 W 20000630; EP 00949235 A 20000630; JP 2001507508 A 20000630; US 1990200 A 20000630