Global Patent Index - EP 1224930 A1

EP 1224930 A1 20020724 - Combination of a SR inhibitor and sigma receptor ligand in the treatment ofdepression

Title (en)

Combination of a SR inhibitor and sigma receptor ligand in the treatment ofdepression

Title (de)

Kombination von einem SR Inhibitoren und einem Sigma Rezeptor Agonisten zur Behandlung von Depressionen

Title (fr)

Combination d'un SRI et d'un ligand du récepteur sigma pour le traitement de la depression

Publication

EP 1224930 A1 20020724 (EN)

Application

EP 02250127 A 20020109

Priority

US 26327801 P 20010122

Abstract (en)

The present invention relates to a method of treating depression, especially refractory depression, in a mammal, including a human, by administering to the mammal a sigma receptor ligand in combination with an antidepressant agent. It also relates to pharmaceutical compositions containing a pharmaceutically acceptable carrier, a sigma receptor ligand and a serotonin reuptake inhibitor.

IPC 1-7

A61K 31/137; A61K 31/4515; A61K 31/485

IPC 8 full level

A61K 31/137 (2006.01); A61K 31/395 (2006.01); A61K 31/4439 (2006.01); A61K 31/4515 (2006.01); A61K 31/4525 (2006.01); A61K 31/485 (2006.01); A61K 31/495 (2006.01); A61K 31/496 (2006.01); A61K 31/4985 (2006.01); A61K 31/506 (2006.01); A61K 31/55 (2006.01); A61K 45/06 (2006.01); A61P 25/24 (2006.01); A61P 43/00 (2006.01)

CPC (source: EP US)

A61K 31/137 (2013.01 - EP US); A61K 31/395 (2013.01 - EP US); A61K 31/4439 (2013.01 - EP US); A61K 31/4515 (2013.01 - EP US); A61K 31/4525 (2013.01 - EP US); A61K 31/485 (2013.01 - EP US); A61K 31/495 (2013.01 - EP US); A61K 31/496 (2013.01 - EP US); A61K 31/4985 (2013.01 - EP US); A61K 31/506 (2013.01 - EP US); A61K 31/55 (2013.01 - EP US); A61K 45/06 (2013.01 - EP US); A61P 25/24 (2017.12 - EP); A61P 43/00 (2017.12 - EP)

Citation (search report)

  • [XY] WO 0041684 A1 20000720 - WARNER LAMBERT CO [US], et al
  • [Y] WO 0050380 A1 20000831 - PFIZER PROD INC [US], et al
  • [PY] WO 0127068 A1 20010419 - PFIZER PROD INC [US], et al
  • [PY] WO 0172687 A1 20011004 - PFIZER LTD [GB], et al
  • [E] WO 0218333 A1 20020307 - PFIZER LTD [GB], et al
  • [E] EP 1184372 A1 20020306 - PFIZER LTD [GB], et al
  • [Y] LEE M-S ET AL: "CO-ADMINISTRATION OF SERTRALINE AND HALOPERIDOL", PSYCHIATRY AND CLINICAL NEUROSCIENCES, BLACKWELL SCIENCE, CARLTON, AU, vol. 52, no. supl, 1998, pages 193 - 198, XP000909378, ISSN: 1323-1316
  • [Y] KINSORA J J ET AL: "EFFECTS OF IGMESINE IN PRECLINICAL ANTIDEPRESSANT TESTS", SOCIETY FOR NEUROSCIENCE ABSTRACTS, SOCIETY FOR NEUROSCIENCE, US, vol. 24, 1998, pages 744, XP000921022, ISSN: 0190-5295
  • [Y] MATSUNO K ET AL: "SA4503: A NOVEL SIGMA1 RECEPTOR AGONIST", CNS DRUG REVIEWS, BRANFORD, CT, US, vol. 4, no. 1, 1998, pages 1 - 24, XP000920761, ISSN: 1080-563X
  • [Y] SORBERA ET AL: "IGMESINE HYDROCHLORIDE", DRUGS OF THE FUTURE, BARCELONA, ES, vol. 24, no. 2, 1999, pages 133 - 140, XP000920774, ISSN: 0377-8282

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

DOCDB simple family (publication)

EP 1224930 A1 20020724; BR 0200155 A 20021015; CA 2368485 A1 20020722; JP 2002226401 A 20020814; MX PA02000800 A 20020918; US 2002099045 A1 20020725; US 6436938 B1 20020820

DOCDB simple family (application)

EP 02250127 A 20020109; BR 0200155 A 20020121; CA 2368485 A 20020118; JP 2002009637 A 20020118; MX PA02000800 A 20020121; US 97361401 A 20011009