EP 1225909 A2 20020731 - FIBROBLAST GROWTH FACTOR-5 (FGF-5) IS A TUMOR ASSOCIATED T-CELL ANTIGEN
Title (en)
FIBROBLAST GROWTH FACTOR-5 (FGF-5) IS A TUMOR ASSOCIATED T-CELL ANTIGEN
Title (de)
FIBROBLASTEN-WACHSTUMSFAKTOR 5 (FGF-5) IST EIN TUMORASSOZIERTES T-ZELL-ANTIGEN
Title (fr)
FACTEUR DE CROISSANCE DES FIBROBLASTES 5 (FGF-5) DANS UN ANTIGENE DE LEUCOCYTE T ASSOCIE AUX TUMEURS
Publication
Application
Priority
- US 0026689 W 20000929
- US 15710399 P 19991002
Abstract (en)
[origin: WO0125271A2] Disclosed herein are methods for treating tumors which express or over-express the tumor associated antigen (TAA) fibroblast growth factor 5 (FGF-5), including renal cell carcinoma (RCC) and carcinoma of the prostate and breast. Methods include modulating an immune response, such as increasing an immune response, or modulating FGF-5 expression or activity. The disclosure also includes methods of determining if a subject has an enhanced susceptibility to a disease associated with abnormal FGF-5 expression.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); A61K 31/7088 (2006.01); A61K 35/14 (2006.01); A61K 35/76 (2006.01); A61K 38/22 (2006.01); A61K 39/00 (2006.01); A61K 39/39 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61P 13/12 (2006.01); A61P 35/00 (2006.01); C07K 14/50 (2006.01); C07K 16/22 (2006.01); C12Q 1/02 (2006.01)
CPC (source: EP)
A61K 39/39 (2013.01); A61K 39/4611 (2023.05); A61K 39/464432 (2023.05); A61P 13/12 (2018.01); A61P 35/00 (2018.01); C07K 14/50 (2013.01); A61K 39/00 (2013.01); A61K 2039/53 (2013.01); A61K 2039/55516 (2013.01); A61K 2039/57 (2013.01); A61K 2239/46 (2023.05)
Citation (examination)
- WO 9730155 A1 19970821 - CHIRON CORP [US]
- WO 9945952 A2 19990916 - GENENTECH INC [US]
- WO 9420125 A1 19940915 - MAX PLANCK GESELLSCHAFT [DE]
- WO 9515176 A1 19950608 - MAX PLANCK GESELLSCHAFT [DE]
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0125271 A2 20010412; WO 0125271 A3 20020510; AU 774958 B2 20040715; AU 7837100 A 20010510; CA 2384696 A1 20010412; EP 1225909 A2 20020731; JP 2003511388 A 20030325
DOCDB simple family (application)
US 0026689 W 20000929; AU 7837100 A 20000929; CA 2384696 A 20000929; EP 00968465 A 20000929; JP 2001528211 A 20000929