EP 1225912 A1 20020731 - A METHOD OF PROPHYLAXIS AND TREATMENT OF AUTOIMMUNE DISEASES, IN PARTICULAR OF DIABETES
Title (en)
A METHOD OF PROPHYLAXIS AND TREATMENT OF AUTOIMMUNE DISEASES, IN PARTICULAR OF DIABETES
Title (de)
METHODE ZUR PROPHYLAXE UND BEHANDLUNG VON AUTOIMMUNERKRANKUNGEN, INSBESONDERE VON DIABETES
Title (fr)
PROCEDE PROPHYLACTIQUE ET DE TRAITEMENT DES MALADIES AUTO-IMMUNES, SPECIFIQUEMENT DU DIABETE
Publication
Application
Priority
- AU 0001299 W 20001020
- AU PQ362799 A 19991022
- AU PQ434799 A 19991126
- AU PQ762100 A 20000519
Abstract (en)
[origin: WO0130378A1] The present invention relates generally to a method of prophylaxis and treatment of autoimmune disease conditions and agents useful for same. In a related embodiment, the present invention contemplates the use of mucosal antigens and/or agents capable of blocking or otherwise delaying cytotoxic T-lymphocyte (CTL) induction and/or maturation to prevent or at least reduce the likelihood or risk of CTL-mediated autoimmune disease. More particularly, the present invention contemplates mucosa-mediated tolerance to protect against or ameliorate the symptoms associated with autoimmune pathology. Even more particularly, the present invention provides a method for preventing clinical insulin-dependent diabetes mellitus (IDDM) or preventing or reducing or ameliorating the effects of clinical IDDM by the aerosol administration of IDDM-associated autoantigens to mucosal surfaces or agents which block CTL induction and/or maturation.
IPC 1-7
A61K 38/28; A61K 39/00; C07K 16/28; A61K 38/19; A61P 3/10; A61P 37/02
IPC 8 full level
A61K 9/12 (2006.01); A61K 39/00 (2006.01); A61K 39/39 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61P 3/10 (2006.01); A61P 37/02 (2006.01); A61P 37/06 (2006.01); C07K 16/28 (2006.01)
CPC (source: EP)
A61K 39/0008 (2013.01); A61P 3/10 (2017.12); A61P 37/02 (2017.12); A61P 37/06 (2017.12); C07K 16/2875 (2013.01); A61K 2039/505 (2013.01); A61K 2039/53 (2013.01); A61K 2039/541 (2013.01)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0130378 A1 20010503; CA 2387652 A1 20010503; EP 1225912 A1 20020731; EP 1225912 A4 20040929; JP 2003512435 A 20030402
DOCDB simple family (application)
AU 0001299 W 20001020; CA 2387652 A 20001020; EP 00972430 A 20001020; JP 2001532795 A 20001020