Global Patent Index - EP 1228045 A2

EP 1228045 A2 20020807 - HETEROCYCLIC CYTOTOXIC AGENTS

Title (en)

HETEROCYCLIC CYTOTOXIC AGENTS

Title (de)

HETEROZYKLISCHE CYTOTOXISCHE WIRKSTOFFE

Title (fr)

AGENTS CYTOTOXIQUES HETEROCYCLIQUES

Publication

EP 1228045 A2 20020807 (EN)

Application

EP 00973917 A 20001026

Priority

  • US 0029583 W 20001026
  • US 16254099 P 19991029

Abstract (en)

[origin: WO0132631A2] The invention provides compounds of formula (I), wherein R1-R8 ang A-G have any of the meanings defined in the specification and their pharmaceutically acceptable salts. The invention also provides pharmaceutical compositions comprising a compound of formula (I), processes for preparing compounds of formula (I), intermediates useful for preparing compounds of formula (I), and therapeutic methods for treating cancer using compounds of formula (I).

IPC 1-7

C07D 237/26; A61K 31/502; A61K 31/5025; A61P 35/00; C07D 491/04; C07D 471/04; C07D 487/04; C07D 471/14

IPC 8 full level

C07D 237/28 (2006.01); A61K 31/5025 (2006.01); A61K 31/517 (2006.01); A61P 31/04 (2006.01); A61P 31/10 (2006.01); A61P 31/12 (2006.01); A61P 33/00 (2006.01); A61P 33/02 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07D 237/26 (2006.01); C07D 471/04 (2006.01); C07D 491/04 (2006.01); C07D 491/056 (2006.01)

CPC (source: EP)

A61P 31/04 (2017.12); A61P 31/10 (2017.12); A61P 31/12 (2017.12); A61P 33/00 (2017.12); A61P 33/02 (2017.12); A61P 35/00 (2017.12); A61P 43/00 (2017.12); C07D 237/26 (2013.01); C07D 471/04 (2013.01); C07D 491/04 (2013.01)

Citation (search report)

See references of WO 0132631A2

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 0132631 A2 20010510; WO 0132631 A3 20020221; AR 026267 A1 20030205; AU 1236401 A 20010514; CA 2389312 A1 20010510; EP 1228045 A2 20020807; JP 2003513079 A 20030408

DOCDB simple family (application)

US 0029583 W 20001026; AR P000105664 A 20001027; AU 1236401 A 20001026; CA 2389312 A 20001026; EP 00973917 A 20001026; JP 2001534782 A 20001026