EP 1233774 A4 20040616 - UROTENSIN-II ANALOGS
Title (en)
UROTENSIN-II ANALOGS
Title (de)
UROTENSIN-II ANALOGA
Title (fr)
ANALOGUES D'UROTENSINE II
Publication
Application
Priority
- US 0032408 W 20001129
- US 16814199 P 19991129
Abstract (en)
[origin: WO0137780A2] The present invention relates generally Urotensin-II analogs and pharmaceutical compositions containing them.
IPC 1-7
IPC 8 full level
A61K 38/00 (2006.01); A61P 1/00 (2006.01); A61P 3/10 (2006.01); A61P 3/12 (2006.01); A61P 5/00 (2006.01); A61P 9/00 (2006.01); A61P 9/04 (2006.01); A61P 9/06 (2006.01); A61P 9/10 (2006.01); A61P 9/12 (2006.01); A61P 11/00 (2006.01); A61P 11/06 (2006.01); A61P 13/00 (2006.01); A61P 15/00 (2006.01); A61P 21/00 (2006.01); A61P 25/00 (2006.01); A61P 25/08 (2006.01); A61P 25/18 (2006.01); A61P 25/22 (2006.01); A61P 25/24 (2006.01); A61P 25/26 (2006.01); A61P 25/30 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); C07K 14/47 (2006.01); C07K 14/575 (2006.01)
CPC (source: EP)
A61P 1/00 (2017.12); A61P 3/10 (2017.12); A61P 3/12 (2017.12); A61P 5/00 (2017.12); A61P 9/00 (2017.12); A61P 9/04 (2017.12); A61P 9/06 (2017.12); A61P 9/10 (2017.12); A61P 9/12 (2017.12); A61P 11/00 (2017.12); A61P 11/06 (2017.12); A61P 13/00 (2017.12); A61P 15/00 (2017.12); A61P 21/00 (2017.12); A61P 25/00 (2017.12); A61P 25/08 (2017.12); A61P 25/18 (2017.12); A61P 25/22 (2017.12); A61P 25/24 (2017.12); A61P 25/26 (2017.12); A61P 25/30 (2017.12); A61P 29/00 (2017.12); A61P 35/00 (2017.12); A61P 43/00 (2017.12); C07K 14/57509 (2013.01); A61K 38/00 (2013.01)
Citation (search report)
- [X] PERKINS T D J ET AL: "Molecular modelling and design of analogues of the peptide hormone Urotensin II", BIOCHEMICAL SOCIETY TRANSACTIONS, COLCHESTER, ESSEX, GB, vol. 18, no. PART 5, October 1990 (1990-10-01), pages 918 - 919, XP002110993, ISSN: 0300-5127
- [Y] CONLON J M ET AL: "ISOLATION AND PRIMARY STRUCTURE OF UROTENSIN II FROM THE BRAIN OF A TETRAPOD, THE FROG RANA RIDIBUNDA", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 188, no. 2, 30 October 1992 (1992-10-30), pages 578 - 583, XP000311226, ISSN: 0006-291X
- [Y] COULOUARN Y ET AL: "Cloning of the cDNA encoding the Urotensin II precursor in frog and human reveals intense expression of the Urotensin II gene in motoneurons of the spinal cord", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 95, no. 26, 22 December 1998 (1998-12-22), pages 15803 - 15808, XP002110994, ISSN: 0027-8424
- [PX] COY D H ET AL: "Novel urotensin II (UII) antagonists point to multiple receptor involvement in UII bioactivity", REGULATORY PEPTIDES, vol. 94, no. 1-3, 25 October 2000 (2000-10-25), 13th International Symposium on Regulatory Peptides;Cairns, Queensland, Australia; October 22-26, 2000, pages 48, XP002267294, ISSN: 0167-0115
- [T] BEHM D J ET AL: "PHARMACOLOGICAL CHARACTERIZATION OF SB-710411 (CPA-CÄD-CYS-PAL-D-TRP-LYS-VAL-CYSÜ-CPA-AMIDE), A NOVEL PEPTIDIC UROTENSIN-II RECEPTOR ANTAGONIST", BRITISH JOURNAL OF PHARMACOLOGY, BASINGSTOKE, HANTS, GB, vol. 137, no. 4, October 2002 (2002-10-01), pages 449 - 458, XP001153544, ISSN: 0007-1188
- [PX] DOUGLAS S A ET AL: "HUMAN UROTENSIN-II, THE MOST POTENT MAMMALIAN VASOCONSTRICTOR IDENTIFIED TO DATE, AS A THERAPEUTIC TARGET FOR THE MANAGEMENT OF CARDIOVASCULAR DISEASE", TRENDS IN CARDIOVASCULAR MEDICINE, ELSEVIER SCIENCE, NEW YORK, NY, US, vol. 10, no. 6, August 2000 (2000-08-01), pages 229 - 237, XP001153538, ISSN: 1050-1738
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0137780 A2 20010531; WO 0137780 A8 20011108; EP 1233774 A1 20020828; EP 1233774 A4 20040616; JP 2003527341 A 20030916
DOCDB simple family (application)
US 0032408 W 20001129; EP 00980842 A 20001129; JP 2001539397 A 20001129