Global Patent Index - EP 1235808 A2

EP 1235808 A2 2002-09-04 - TRICYCLIC ANALGESICS

Title (en)

TRICYCLIC ANALGESICS

Title (de)

TRIZYCLISCHE ANALGETIKA

Title (fr)

ANALGESIQUES TRICYCLIQUES

Publication

EP 1235808 A2 (EN)

Application

EP 00951290 A

Priority

  • EP 0005783 W
  • US 13786899 P

Abstract (en)

[origin: WO0075116A2] A tricyclic compound of Formula (I): wherein: R<1> is hydrogen or hydroxy; R<2> is hydrogen or hydroxy; or R<1> and R<2> together are oxygen; A is a bond, CH2, CH CH3, CH2 CH2 or C(CH3)2; R<3> and R<4> are the same or different and are hydrogen, halo, C1-C6 alkyl, C1-C4 alkoxy, trifluoromethyl, NO2, COR<6>, COOR<6> or NR<6>R<7>, wherein R<6> and R<7> are the same or different and are hydrogen, C1-C6 alkyl or benzyl; R<5> is hydrogen, C1-6 alkyl, C2-6 alkenyl, C3-6 cycloalkyl, (O=C)-C1-6 alkyl, (O=C)-C2-6 alkenyl, (O=C)-C3-6 cycloalkyl, wherein said alkyl, alkenyl and cycloalkyl groups can be substituted by 1, 2 or 3 groups selected from halo, C3-C6 cycloalkyl, phenyl or substituted phenyl, and salts thereof, are particularly useful for treating, among other indications, neuropathic pain and other CNS disorders.

IPC 1-7 (main, further and additional classification)

C07D 221/20; A61K 31/438; A61P 25/00

IPC 8 full level (invention and additional information)

A61K 31/438 (2006.01); A61P 25/00 (2006.01); A61P 29/02 (2006.01); C07D 221/00 (2006.01); C07D 221/20 (2006.01)

CPC (invention and additional information)

C07D 221/20 (2013.01)

Citation (search report)

See references of WO 0075116A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 0075116 A2 20001214; WO 0075116 A3 20020704; AP 200102356 A0 20011231; AU 6428400 A 20001228; BG 106162 A 20020531; BR 0011427 A 20020326; CA 2376076 A1 20001214; CN 1635998 A 20050706; EA 200101117 A1 20020627; EP 1235808 A2 20020904; HR P20010913 A2 20030430; HU 0203317 A2 20030228; IL 146755 D0 20020725; IS 6175 A 20011123; JP 2003513006 A 20030408; MA 26795 A1 20041220; MX PA01012694 A 20031015; NO 20015966 A 20011206; NO 20015966 D0 20011206; PL 357340 A1 20040726; SK 17512001 A3 20021106; TR 200103531 T2 20020621

INPADOC legal status


2007-06-27 [18D] APPLICATION DEEMED TO BE WITHDRAWN

- Effective date: 20070102

2007-02-21 [RAP1] TRANSFER OF RIGHTS OF AN APPLICATION

- Owner name: WARNER-LAMBERT COMPANY LLC

2004-03-10 [RAP1] TRANSFER OF RIGHTS OF AN APPLICATION

- Owner name: WARNER-LAMBERT COMPANY LLC

2003-05-21 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20030219

2002-09-04 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2002-09-04 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO:

- Free text: AL;LT;LV;MK;RO;SI