Global Patent Index - EP 1235910 A1

EP 1235910 A1 2002-09-04 - PLANT VIRUS PARTICLES WITH EXOGENOUS INTERNAL EITOPES

Title (en)

PLANT VIRUS PARTICLES WITH EXOGENOUS INTERNAL EITOPES

Title (de)

PFLANZLICHE VIRUSPARTIKEL MIT EXOGENEN EPITOPEN AN DER INNEREN FLÄCHE

Title (fr)

PARTICULES VIRALES COMPORTANT DES EPITOPES INTERNES EXOGENES

Publication

EP 1235910 A1 (EN)

Application

EP 00972153 A

Priority

  • GB 9924352 A
  • US 0028430 W

Abstract (en)

[origin: WO0127282A1] The present invention relates to the expression of peptides on viral particles, and more particularly to the expression of peptides on the interior of the viral capsid. Methods are described for modifying viruses so that exogenous epitopes are expressed on the interior of the viral capsid. Viruses that can be modified include (+) stranded RNA viruses, especially plant (+) stranded RNA viruses such as the cowpea mosaic virus. Internal expression is especially useful for the expression of hydrophobic epitopes. The modified viral particles also find use as vaccines and as such are capable of eliciting an immune response.

IPC 1-7 (main, further and additional classification)

C12N 15/40; A61K 39/00; C07K 14/08; C12N 7/01; C12N 15/62

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); A61K 39/12 (2006.01); A61P 31/12 (2006.01); C07K 14/02 (2006.01); C07K 14/08 (2006.01); C07K 14/12 (2006.01); C07K 14/145 (2006.01); C12N 7/00 (2006.01); C12N 7/01 (2006.01); C12N 15/40 (2006.01); C12N 15/82 (2006.01)

CPC (invention and additional information)

C07K 14/005 (2013.01); C12N 15/8203 (2013.01); C12N 15/8257 (2013.01); A61K 2039/57 (2013.01); C07K 2319/00 (2013.01); C12N 2730/10122 (2013.01); C12N 2760/18722 (2013.01); C12N 2760/20122 (2013.01)

Citation (search report)

See references of WO 0127282A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 0127282 A1 20010419; WO 0127282 A8 20010816; AR 026066 A1 20021226; AU 1085201 A 20010423; AU 785020 B2 20060824; BR 0014861 A 20020716; CA 2387626 A1 20010419; CN 101591647 A 20091202; CN 1471580 A 20040128; CO 5280142 A1 20030530; CZ 20021303 A3 20021016; EP 1235910 A1 20020904; GB 9924352 D0 19991215; IL 149077 D0 20021110; JP 2003534771 A 20031125; MX PA02003789 A 20020930; PL 354933 A1 20040322; ZA 200202815 B 20030827

INPADOC legal status


2011-07-27 [18D] APPLICATION DEEMED TO BE WITHDRAWN

- Effective date: 20110104

2010-05-12 [RAP1] TRANSFER OF RIGHTS OF AN APPLICATION

- Owner name: PFENEX, INC.

2003-09-24 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20030808

2002-09-04 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20020514

2002-09-04 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2002-09-04 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO:

- Free text: AL;LT;LV;MK;RO;SI