EP 1235910 A1 20020904 - PLANT VIRUS PARTICLES WITH EXOGENOUS INTERNAL EITOPES
Title (en)
PLANT VIRUS PARTICLES WITH EXOGENOUS INTERNAL EITOPES
Title (de)
PFLANZLICHE VIRUSPARTIKEL MIT EXOGENEN EPITOPEN AN DER INNEREN FLÄCHE
Title (fr)
PARTICULES VIRALES COMPORTANT DES EPITOPES INTERNES EXOGENES
Publication
Application
Priority
- GB 9924352 A 19991014
- US 0028430 W 20001013
Abstract (en)
[origin: WO0127282A1] The present invention relates to the expression of peptides on viral particles, and more particularly to the expression of peptides on the interior of the viral capsid. Methods are described for modifying viruses so that exogenous epitopes are expressed on the interior of the viral capsid. Viruses that can be modified include (+) stranded RNA viruses, especially plant (+) stranded RNA viruses such as the cowpea mosaic virus. Internal expression is especially useful for the expression of hydrophobic epitopes. The modified viral particles also find use as vaccines and as such are capable of eliciting an immune response.
IPC 1-7
IPC 8 full level
A61K 39/12 (2006.01); A61P 31/12 (2006.01); C07K 14/02 (2006.01); C07K 14/08 (2006.01); C07K 14/12 (2006.01); C07K 14/145 (2006.01); C12N 7/00 (2006.01); C12N 7/01 (2006.01); C12N 15/09 (2006.01); C12N 15/40 (2006.01); C12N 15/82 (2006.01)
CPC (source: EP KR)
A61P 31/12 (2017.12 - EP); C07K 14/005 (2013.01 - EP); C12N 15/11 (2013.01 - KR); C12N 15/8203 (2013.01 - EP); C12N 15/8257 (2013.01 - EP); A61K 2039/57 (2013.01 - EP); C07K 2319/00 (2013.01 - EP); C12N 2730/10122 (2013.01 - EP); C12N 2760/18722 (2013.01 - EP); C12N 2760/20122 (2013.01 - EP)
Citation (search report)
See references of WO 0127282A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0127282 A1 20010419; WO 0127282 A8 20010816; AR 026066 A1 20021226; AU 1085201 A 20010423; AU 785020 B2 20060824; BR 0014861 A 20020716; CA 2387626 A1 20010419; CN 101591647 A 20091202; CN 1471580 A 20040128; CO 5280142 A1 20030530; CZ 20021303 A3 20021016; EP 1235910 A1 20020904; GB 9924352 D0 19991215; IL 149077 A0 20021110; JP 2003534771 A 20031125; KR 100880477 B1 20090128; KR 20020040868 A 20020530; MX PA02003789 A 20020930; PL 354933 A1 20040322; ZA 200202815 B 20030827
DOCDB simple family (application)
US 0028430 W 20001013; AR P000105455 A 20001017; AU 1085201 A 20001013; BR 0014861 A 20001013; CA 2387626 A 20001013; CN 00816753 A 20001013; CN 200910142626 A 20001013; CO 00078905 A 20001017; CZ 20021303 A 20001013; EP 00972153 A 20001013; GB 9924352 A 19991014; IL 14907700 A 20001013; JP 2001530485 A 20001013; KR 20027004778 A 20020413; MX PA02003789 A 20001013; PL 35493300 A 20001013; ZA 200202815 A 20020410