Global Patent Index - EP 1235922 A2

EP 1235922 A2 2002-09-04 - EXCIPIENT SYSTEM THAT CONTAINS COATING SUBSTANCES WITH ENZYMATICALLY REMOVABLE SIDE-GROUPS

Title (en)

EXCIPIENT SYSTEM THAT CONTAINS COATING SUBSTANCES WITH ENZYMATICALLY REMOVABLE SIDE-GROUPS

Title (de)

TRÄGERSYSTEME, ENTHALTEND HÜLLSUBSTANZEN MIT ENZYMATISCH ABSPALTBAREN SEITENGRUPPEN

Title (fr)

SYSTEMES PORTEURS COMPORTANT DES SUBSTANCES ENVELOPPANTES AVEC GROUPES LATERAUX POUVANT ETRE SEPARES DE MANIERE ENZYMATIQUE

Publication

EP 1235922 A2 (DE)

Application

EP 00977515 A

Priority

  • DE 19956029 A
  • EP 0011055 W

Abstract (en)

[origin: DE19956029A1] A carrier system for active substances is based on coating a substance with enzymatically cleavable anionic side groups which determine the stability of the system and which, when cleaved, result in collapse of the system and liberation of the active substance. A carrier system is obtained by the admixture of component (b1) with either component (a1) or a complex obtained from component (a1) and component (a2) in a molar ratio of 1:1-0000, with the components being admixed in amounts to provide a finished complex which is preferably neutral or anionic. Component (a1) comprises an active substance (a1) and a binding structure (a1) (which can be part of the active substance) for binding structure (b1) or (a2). Component (a2) comprises a carrier (a2) and a binding structure (a2) (which can be part of the carrier) for binding structure (a1), and component (b1) comprises a binding structure (b1) for binding structure (a1), active substance (a1), carrier (a2) or binding structure (a2), a coating substance which can contain the binding structure (b1), an enzymatically cleavable linking member and an anionic side group.

IPC 1-7 (main, further and additional classification)

C12N 15/88; A61K 31/70; A61K 47/42; A61K 48/00

IPC 8 full level (invention and additional information)

A61K 47/48 (2006.01); A61K 9/127 (2006.01); A61K 47/26 (2006.01); A61K 47/30 (2006.01); A61K 47/42 (2006.01); A61K 48/00 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01); C12N 15/88 (2006.01); A61K 38/00 (2006.01)

CPC (invention and additional information)

C12N 15/88 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01); A61K 2121/00 (2013.01)

Citation (search report)

See references of WO 0138552A3

Designated contracting state (EPC)

DE ES FR GB IT

EPO simple patent family

DE 19956029 A1 20010523; AU 1520201 A 20010604; CA 2391922 A1 20010531; EP 1235922 A2 20020904; JP 2003514895 A 20030422; MX PA02004532 A 20020902; WO 0138552 A2 20010531; WO 0138552 A3 20020328

INPADOC legal status


2004-05-19 [RBV] DESIGNATED CONTRACTING STATES (CORRECTION)

- Designated State(s): DE ES FR GB IT

2003-07-30 [18W] APPLICATION WITHDRAWN

- Effective date: 20030602

2002-11-27 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20020930

2002-09-04 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

2002-09-04 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO:

- Free text: AL;LT;LV;MK;RO;SI