EP 1237903 A1 20020911 - 11-BETA-PHENYLESTRADIENE DERIVATIVES WITH FLUOROALKYL GROUPS IN THE AROMATIC SIDE CHAIN, PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS

Title (en)

11-BETA-PHENYLESTRADIENE DERIVATIVES WITH FLUOROALKYL GROUPS IN THE AROMATIC SIDE CHAIN, PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS

Title (de)

11-BETA-PHENYLESTRADIEN-DERIVATE MIT FLUORALKYLGRUPPEN IN DER AROMATISCHEN SEITENKETTE, DEREN HERSTELLUNG UND DIESE VERBINDUNGEN ENTHALTENDE PHARMAZEUTISCHE ZUSAMMENSETZUNGEN

Title (fr)

DERIVES DE 11-BETA-PHENYLESTRADIENE AYANT DES GROUPES FLUORO-ALKYLE DANS LA CHAINE LATERALE AROMATIQUE, LEUR PRODUCTION ET DES COMPOSITIONS PHARMACEUTIQUES CONTENANT CES COMPOSES

Publication

EP 1237903 A1 20020911 (DE)

Application

EP 00988736 A 20001121

Priority

DE 19961219 A 19991215
EP 0011556 W 20001121

Abstract (en)

[origin: WO0144267A1] The invention relates to novel 11- beta -phenylestradiene derivatives with fluoroalkyl groups in the aromatic side chain, of general formula (I), to a method for producing them and to pharmaceutical preparations containing these compounds. The inventive compounds are suitable for treating diseases that are stimulated by cortisol or corticoids, for reducing the secreted cortisol, for stimulating lactation, for treating dysmenorrhea and myomas, for treating Cushing's disease and for cervical maturation, for improving cognitive performance, for treating endometriosis or for hormone replacement therapy (HRT).

IPC 1-7

C07J 41/00; C07J 1/00; A61K 31/565

IPC 8 full level

A61K 31/567 (2006.01); A61P 5/24 (2006.01); A61P 5/38 (2006.01); A61P 13/12 (2006.01); A61P 15/00 (2006.01); A61P 15/14 (2006.01); C07J 1/00 (2006.01); C07J 41/00 (2006.01)

CPC (source: EP)

A61P 5/24 (2017.12); A61P 5/38 (2017.12); A61P 13/12 (2017.12); A61P 15/00 (2017.12); A61P 15/14 (2017.12); C07J 1/0081 (2013.01); C07J 41/0083 (2013.01)

Citation (search report)

See references of WO 0144267A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

DOCDB simple family (publication)

WO 0144267 A1 20010621; AU 2507601 A 20010625; DE 19961219 A1 20010719; EP 1237903 A1 20020911; JP 2003517001 A 20030520

DOCDB simple family (application)

EP 0011556 W 20001121; AU 2507601 A 20001121; DE 19961219 A 19991215; EP 00988736 A 20001121; JP 2001544756 A 20001121