Global Patent Index - EP 1238069 A2

EP 1238069 A2 2002-09-11 - ANTISENSE OLIGONUCLEOTIDES FOR METABOTROPIC GLUTAMATE RECEPTOR TYPE 1 (MGLUR1)

Title (en)

ANTISENSE OLIGONUCLEOTIDES FOR METABOTROPIC GLUTAMATE RECEPTOR TYPE 1 (MGLUR1)

Title (de)

ANTISENSE OLIGONUCLEOTIDEN FÜR MGLUR1

Title (fr)

OLIGONUCLEOTIDES DE RECEPTEUR TYPE 1 DE GLUTAMATE METABOTROPIQUE (MGLUR1)

Publication

EP 1238069 A2 (EN)

Application

EP 00945507 A

Priority

  • CA 0000824 W
  • US 14400499 P

Abstract (en)

[origin: WO0105963A2] The present invention relates to antisense oligonucleotides for metabotropic glutamate receptor type 1 (mGluR1). There is provided oligonucleotides that hybridize to a mRNA encoding mGluR1 or a splice variant thereof. There is also provided a method for treating a patient having a disorder related to an elevated glutamate level, such as chronic pain, or to enhance an opioid effect or to reduce opioid dependence and/or tolerance, which comprises the administration of such an oligonucleotide. Specific pain treatment is thereby obtained.

IPC 1-7 (main, further and additional classification)

C12N 15/11

IPC 8 full level (invention and additional information)

C12N 15/113 (2010.01); A61K 38/00 (2006.01)

CPC (invention and additional information)

C12N 15/1138 (2013.01); A61K 38/00 (2013.01); C12N 2310/312 (2013.01); C12N 2310/3125 (2013.01); C12N 2310/315 (2013.01); C12N 2310/3511 (2013.01)

Citation (search report)

See references of WO 0105963A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 0105963 A2 20010125; WO 0105963 A3 20011108; AU 5959900 A 20010205; CA 2377937 A1 20010125; EP 1238069 A2 20020911

INPADOC legal status


2004-08-11 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20040201

2002-09-11 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20020208

2002-09-11 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2002-09-11 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Free text: AL;LT;LV;MK;RO;SI